{"title":"急性肝衰竭","authors":"James Beck, Jasleen K Bolina, Lisa H Boyd","doi":"10.1097/01.JAA.0000000000000001","DOIUrl":null,"url":null,"abstract":"<p><strong>Abstract: </strong>Acute liver failure, commonly caused by acetaminophen overdose, is associated with numerous systemic complications including cerebral edema, hypotension, acute kidney injury, and infection. Management is primarily supportive, with an emphasis on excellent neurocritical care. Although some antidotes and targeted treatments exist, the only definitive treatment remains orthotopic liver transplant.</p>","PeriodicalId":48728,"journal":{"name":"Jaapa-Journal of the American Academy of Physician Assistants","volume":null,"pages":null},"PeriodicalIF":0.8000,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Acute liver failure.\",\"authors\":\"James Beck, Jasleen K Bolina, Lisa H Boyd\",\"doi\":\"10.1097/01.JAA.0000000000000001\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Abstract: </strong>Acute liver failure, commonly caused by acetaminophen overdose, is associated with numerous systemic complications including cerebral edema, hypotension, acute kidney injury, and infection. Management is primarily supportive, with an emphasis on excellent neurocritical care. Although some antidotes and targeted treatments exist, the only definitive treatment remains orthotopic liver transplant.</p>\",\"PeriodicalId\":48728,\"journal\":{\"name\":\"Jaapa-Journal of the American Academy of Physician Assistants\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.8000,\"publicationDate\":\"2024-05-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Jaapa-Journal of the American Academy of Physician Assistants\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1097/01.JAA.0000000000000001\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2024/4/25 0:00:00\",\"PubModel\":\"Epub\",\"JCR\":\"Q3\",\"JCRName\":\"MEDICINE, GENERAL & INTERNAL\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Jaapa-Journal of the American Academy of Physician Assistants","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1097/01.JAA.0000000000000001","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2024/4/25 0:00:00","PubModel":"Epub","JCR":"Q3","JCRName":"MEDICINE, GENERAL & INTERNAL","Score":null,"Total":0}
Abstract: Acute liver failure, commonly caused by acetaminophen overdose, is associated with numerous systemic complications including cerebral edema, hypotension, acute kidney injury, and infection. Management is primarily supportive, with an emphasis on excellent neurocritical care. Although some antidotes and targeted treatments exist, the only definitive treatment remains orthotopic liver transplant.
期刊介绍:
JAAPA is the peer-reviewed clinical journal of the American Academy of Physician Assistants (AAPA). Published for more than 25 years, its mission is to support the ongoing education and advancement of physician assistants (PAs) by publishing current information and research on clinical, health policy, and professional issues.
Published monthly, JAAPA''s award-winning editorial includes:
-Clinical review articles (with AAPA-approved Category I CME in each issue)-
Case reports-
Clinical departments-
Original health services research-
Articles on issues of professional interest to PAs