子宫内膜厚度对胚胎移植后妊娠结果的影响:回顾性队列

IF 1.8 Q3 OBSTETRICS & GYNECOLOGY
Aghdas Safari, Foruheh Moazzezi, Mohammad Azizi
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引用次数: 0

摘要

目的:辅助生殖技术的安全性可通过将出生体重作为一项结果指标来评估。本研究旨在评估胚胎移植过程中子宫内膜厚度对新生儿出生体重和早产的影响:我们在一所医科大学附属教学医院的不孕不育科进行了一项回顾性队列研究。符合条件的女性年龄≥18 岁,通过胚胎移植单胎妊娠,子宫内膜厚度≥7 毫米。患者均无糖尿病、高血压和多囊卵巢综合征。我们评估了母体和新生儿的特征以及围产期妊娠结局:共纳入了 100 名符合条件的患者,平均(标清)年龄为 32.8(6.2)岁。胚胎移植时的平均子宫内膜厚度为 9.1 (1.2) 毫米,平均出生体重为 3040.7 (565.3) 克。子宫内膜厚度与早产(P=0.215)、子宫内膜厚度与死胎或胎儿宫内死亡(P=0.880)之间没有统计学意义。然而,在调整了混杂因素后,子宫内膜厚度与出生体重的关系具有统计学意义[b=124.6 (51.6),p=0.018]:结论:在≥7毫米的范围内,胚胎移植时的子宫内膜厚度是新生儿体重的预测指标;但它与早产、死胎或胎儿宫内死亡的风险无关。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
The effects of endometrial thickness on outcomes of pregnancy following embryo transfer: A retrospective cohort.

Objective: The safety of assisted reproductive technology can be assessed by examining birth weight as an outcome measure. The objective of this study was to evaluate the effect of endometrial thickness during embryo transfer on newborn birth weight and preterm labor.

Methods: We conducted a retrospective cohort study at the infertility department of a teaching hospital affiliated with a university of medical sciences. Eligible women were ≥18 years old and conceived a singleton pregnancy with embryo transfer and an endometrial thickness of ≥7 mm. None of the patients had diabetes, blood hypertension, and polycystic ovarian syndrome. We assessed maternal and newborn characteristics and perinatal pregnancy outcomes.

Results: In total, 100 eligible patients with a mean (SD) age of 32.8 (6.2) years were included. The mean endometrial thickness during embryo transfer was 9.1 (1.2) mm, and the mean birth weight was 3040.7 (565.3)g. There were no statistically significant associations between endometrial thickness and preterm labor (p=0.215) and between endometrial thickness and stillbirth or intra-uterine fetal death (p=0.880). However, after adjusting for confounding factors, the association of endometrial thickness with birth weight was statistically significant [b=124.6 (51.6), p=0.018].

Conclusions: Within the range of ≥7mm, endometrial thickness during embryo transfer is a predictor of newborn weight; however, it is not related to the risk of preterm labor, stillbirth, or intra-uterine fetal death.

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来源期刊
CiteScore
3.30
自引率
6.70%
发文量
56
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