轻链多发性骨髓瘤的浆细胞性骨髓瘤转化。

IF 0.9 Q4 HEMATOLOGY

Journal of Clinical and Experimental Hematopathology Pub Date : 2024-06-27 Epub Date: 2024-04-30 DOI:10.3960/jslrt.24004

Nagehan Pakasticali, Glen L Hortin, Julie Y Li

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引用次数: 0

摘要

浆细胞性骨髓瘤（PBM）是多发性骨髓瘤（MM）的一种不常见的侵袭性形态变异。肿瘤未成熟细胞表现出多种形态，给诊断带来了挑战。PBM的诊断标准包括在骨髓抽吸物中发现≥2%的浆细胞。本病例描述了偶然发现的轻链多发性骨髓瘤（LCMM）转化为 PBM 的情况，这种现象以前从未报道过。

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Plasmablastic myeloma transformation of light-chain multiple myeloma.

Plasmablastic myeloma (PBM) is an uncommon and aggressive morphologic variant of multiple myeloma (MM). The neoplastic immature cells exhibit diverse morphology, posing a diagnostic challenge. The diagnostic criteria for PBM include the identification of ≥ 2% plasmablasts in the bone marrow aspirate. This case describes the incidental finding of a light-chain multiple myeloma (LCMM) transformed into PBM, a phenomenon not previously reported.

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来源期刊

Journal of Clinical and Experimental Hematopathology HEMATOLOGY-

CiteScore

2.00

自引率

6.70%

发文量

审稿时长

11 weeks