皮秒紫翠宝石激光治疗儿童太田痣。

IF 2.2 3区 医学 Q2 DERMATOLOGY
Wenwen Zhao BSN, Ying Yang MD, Hualing Shi BSN, Lifang Guo MD, Hui Ding MD, Huiying Zhen MD, Tong Lin MD, Yiping Ge MD
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引用次数: 0

摘要

背景介绍皮秒紫翠宝石激光已被安全有效地用于治疗成人太田痣。然而,用于儿童的数据有限:研究 755nm 皮秒紫翠宝石激光治疗儿童太田痣的疗效、安全性及相关影响因素:我们回顾性分析了在一家三级皮肤病医院接受 755nm 皮秒紫翠宝石激光治疗的中国太田痣患儿:共有 305 名儿童患者接受了平均两次治疗,色素清除率平均达到 79%。第一次治疗后,22 名患者达到完全清除(95%-100%),72 名患者达到极佳反应(75%-94%),平均初始疗效为病灶清除率 63%。早期治疗取得了更好的初始疗效(0至12个月组>1至6年组,6至12年组)。0至12个月组的最终疗效更好。治疗次数越多,最终疗效越好。治疗颜色较深的病灶时,初始疗效和最终疗效都更好。并发症发生率为12.1%,其中10.8%为炎症后色素沉着,1.3%为色素减退。复发率为 6.6%:局限性:回顾性研究:755nm皮秒紫翠宝石激光治疗儿童太田痣安全有效。开始治疗的年龄越小、皮损颜色越深、治疗次数越多,色素清除率越高。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Picosecond alexandrite laser treatment of nevus of Ota in children

Background

The picosecond alexandrite laser has been safely and effectively used to treat the nevus of Ota in adults. However, limited data are available for children.

Objective

To investigate the efficacy, safety, and correlative influencing factors of a 755nm picosecond alexandrite laser in the treatment of nevus of Ota in children.

Methods

We retrospectively analyzed Chinese children with nevus of Ota who received a 755nm picosecond alexandrite laser treatment in a tertiary dermatological hospital.

Result

A total of 305 pediatric patients received an average of two treatments achieving an average of 79% pigment clearance. After the first treatment, 22 patients achieved complete clearance (95%–100%), and 72 patients achieved excellent response (75%–94%), with an average initial efficacy of 63% lesion clearance. Treatment at an early age achieved better initial efficacy (0- to 12-month group >1- to 6-year group, 6- to 12-year group). And 0- to 12-month group achieved better final efficacy. More treatment sessions also increased the final efficacy. Both initial efficacy and final efficacy were better when treating a darker lesion. The incidence of complications was 12.1%, with 10.8% being post-inflammatory hyperpigmentation and 1.3% being hypopigmentation. The rate of recurrence was 6.6%.

Limitation

Retrospective study.

Conclusion

A 755nm picosecond alexandrite laser is safe and effective in treating nevus of Ota in children. Younger to initiate treatment, darker lesions, and more treatments are positively associated with better pigmentation clearance.

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来源期刊
CiteScore
5.40
自引率
12.50%
发文量
119
审稿时长
1 months
期刊介绍: Lasers in Surgery and Medicine publishes the highest quality research and clinical manuscripts in areas relating to the use of lasers in medicine and biology. The journal publishes basic and clinical studies on the therapeutic and diagnostic use of lasers in all the surgical and medical specialties. Contributions regarding clinical trials, new therapeutic techniques or instrumentation, laser biophysics and bioengineering, photobiology and photochemistry, outcomes research, cost-effectiveness, and other aspects of biomedicine are welcome. Using a process of rigorous yet rapid review of submitted manuscripts, findings of high scientific and medical interest are published with a minimum delay.
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