脑动静脉畸形的治疗。

Vladimír Beneš, Adéla Bubeníková, Petr Skalický, Ondřej Bradáč
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引用次数: 0

摘要

脑动静脉畸形(AVM)是一种罕见的血管畸形,其特点是动脉血直接流入静脉循环的解剖分流。积极治疗脑动静脉畸形的主要目的是预防出血。目前有一些行之有效的治疗策略,其安全性和有效性不断提高,这主要归功于成像模式、靶向和新型技术的进步,替代治疗方法的开发,以及对疾病本身更丰富的经验。一些有趣的成像新技术可用于颅内 AVM 患者决策和规划最有效的治疗方法。手术通常被认为是第一线治疗方法;然而,每个患者都应进行单独评估,积极治疗政策的风险不应超过疾病自发自然病史的益处。所有治疗方式,即手术、放射外科手术、血管内栓塞和观察,都有其合理性,但需要根据每位患者的具体情况进行精心选择,以达到最佳治疗效果。本章介绍了历史上和当前应用的教条,随后介绍了 AVM 管理中每种可用治疗方式的进展。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Treatment of Brain Arteriovenous Malformations.

Brain arteriovenous malformations (AVMs) are a rare entity of vascular anomalies, characteristic of anatomical shunting where arterial blood directly flows into the venous circulation. The main aim of the active treatment policy of brain AVMs is the prevention of haemorrhage. There are well-established treatment strategies that continually improve in their safety and efficacy, primarily due to the advances in imaging modalities, targeted and novel techniques, the development of alternative treatment approaches, and even better experience with the disease itself. There are interesting imaging novelties that may be prospectively applicable in the decision-making and planning of the most effective treatment approach for individual patients with intracranial AVM. Surgery is often considered the first-line treatment; however, each patient should be evaluated individually, and the risks of the active treatment policy should not overcome the benefits of the spontaneous natural history of the disease. All treatment modalities, i.e., surgery, radiosurgery, endovascular embolization, and observation, are justified but need to be meticulously selected for each individual patient in order to deliver the best treatment outcome. This chapter deals with historical and currently applied dogmas, followed by introductions of advances in each available treatment modality of AVM management.

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