影响乳腺癌微环境异质性的因素：叙事性微型综述。

3区生物学 Q1 Biochemistry, Genetics and Molecular Biology

International review of cell and molecular biology Pub Date : 2024-01-01 Epub Date: 2024-02-15 DOI:10.1016/bs.ircmb.2024.01.002

Anirban Ganguly, Sumit Mukherjee, Kaushiki Chatterjee, Sheila Spada

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引用次数: 0

摘要

乳腺癌（BC）的异质性是BC肿瘤的一个关键特征，对肿瘤发生、诊断和治疗方法具有重要影响。异质性受肿瘤内在特征和不同瘤内区域肿瘤微环境（TME）组成的影响，进而影响患者的癌症进展。在这篇小型综述中，我们将重点介绍 BC 癌症异质性的产生机制，以及它们如何影响癌症疗法的反应。

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Factors affecting heterogeneity in breast cancer microenvironment: A narrative mini review.

Breast cancer (BC) heterogeneity is a key trait of BC tumors with crucial implications on tumorigenesis, diagnosis, and therapeutic modalities. It is influenced by tumor intrinsic features and by the tumor microenvironment (TME) composition of different intra-tumoral regions, which in turn affect cancer progression within patients. In this mini review, we will highlight the mechanisms that generate cancer heterogeneity in BC and how they affect the responses to cancer therapies.

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来源期刊

International review of cell and molecular biology BIOCHEMISTRY & MOLECULAR BIOLOGY-CELL BIOLOGY

CiteScore

7.70

自引率

0.00%

发文量

审稿时长

>12 weeks

期刊介绍： International Review of Cell and Molecular Biology presents current advances and comprehensive reviews in cell biology-both plant and animal. Articles address structure and control of gene expression, nucleocytoplasmic interactions, control of cell development and differentiation, and cell transformation and growth. Authored by some of the foremost scientists in the field, each volume provides up-to-date information and directions for future research.