下肢慢性静脉疾病患者的动脉危险因素和踝肱指数特征：BEST 研究结果。

IF 1.5 4区医学 Q3 PERIPHERAL VASCULAR DISEASE

International Angiology Pub Date : 2024-04-01 Epub Date: 2024-04-12 DOI:10.23736/S0392-9590.24.05142-3

Shangtong Jiang, Yue Liu, Jinbo Liu, Gaoqiang Xie, Hongwei Zhao, Na Zhao, Hongyu Wang

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引用次数: 0

摘要

研究背景我们的研究旨在探讨下肢慢性静脉疾病（LECVD）患者的动脉危险因素和踝肱指数（ABI）的特征：方法：本研究共纳入 2642 名受试者。方法：我们共对 2642 名受试者进行了研究，收集了他们的生活方式和临床数据。血管疾病史包括冠心病、中风、高血压和糖尿病。ABI低于0.9为下肢动脉疾病（LEAD）。测量了一系列血液指标：结果：ABI 低于 0.9 的患者属于 LEAD 组。年龄、吸烟、饮酒、高血压、糖尿病、降脂药、抗糖尿病药、总蛋白、总蛋白、甘油三酯、低密度脂蛋白胆固醇、糖化血红蛋白和同型半胱氨酸是 LEAD 和 LECVD 的共同危险因素：我们的研究表明，ABI 低于 0.9 是导致 LECVD 的独立危险因素。

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The characteristics of arterial risk factors and ankle-brachial index in patients with lower extremity chronic venous diseases: results from the BEST study.

Background: The aim of our study was to explore the characteristics of the arterial risk factors and ankle-brachial index (ABI) in patients with lower extremity chronic venous disease (LECVD).

Methods: A total of 2642 subjects were employed in our study. The lifestyle and clinical data were collected. The history of vascular diseases contained coronary artery disease, stroke, hypertension, and diabetes. ABI low than 0.9 was considered as lower extremity artery disease (LEAD). A series of blood indicators were measured.

Results: Patients with ABI low than 0.9 belonged to the group of LEAD. Age, smoking, drinking, hypertension, diabetes mellitus, lipid-lowering drug, antidiabetic, total protein, total protein, triglyceride, low-density lipoprotein cholesterol, glycosylated hemoglobin and homocysteine were the common risk factors shared by LEAD and LECVD (P<0.05). The prevalence of LEAD in patients with LECVD was higher than those without LECVD (P<0.05). In Pearson correlation analysis, LECVD was related to LEAD (P<0.05). Before and after adjusted shared factors, as the performance of the logistic regression models, LEAD was an independent risk factor for the prevalence of LECVD (OR=2.937, 95% CI: [1.956, 4.411], P<0.001).

Conclusions: Our study demonstrated that an ABI lower than 0.9 is an independent risk factor for LECVD.

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来源期刊

International Angiology 医学-外周血管病

CiteScore

2.80

自引率

28.60%

发文量

审稿时长

6-12 weeks

期刊介绍： International Angiology publishes scientific papers on angiology. Manuscripts may be submitted in the form of editorials, original articles, review articles, special articles, letters to the Editor and guidelines. The journal aims to provide its readers with papers of the highest quality and impact through a process of careful peer review and editorial work. Duties and responsibilities of all the subjects involved in the editorial process are summarized at Publication ethics. Manuscripts are expected to comply with the instructions to authors which conform to the Uniform Requirements for Manuscripts Submitted to Biomedical Editors by the International Committee of Medical Journal Editors (ICMJE).