COVID-19 隔离病房爆发耐碳青霉烯类鲍曼不动杆菌疫情,感染控制措施成功控制了疫情。

IF 2.8 Q2 INFECTIOUS DISEASES
Infection and Chemotherapy Pub Date : 2024-06-01 Epub Date: 2024-03-27 DOI:10.3947/ic.2023.0091
Ki Hyun Lee, Jinnam Kim, Jung Ah Lee, Chang Hyup Kim, Oh Mi Kwon, Eun Ju You, Hyuk Min Lee, Jung Ho Kim, Su Jin Jeong, Nam Su Ku, Joon-Sup Yeom, Jin Young Ahn, Jun Yong Choi
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引用次数: 0

摘要

背景:即使在冠状病毒病-19(COVID-19)大流行期间,耐多药细菌的传播和感染控制仍是一项重要任务。在确认 COVID-19 隔离室爆发耐碳青霉烯类鲍曼不动杆菌(CRAB)疫情后,我们想介绍一下采取了哪些感染控制措施来根除这一疫情:分析了 2021 年 10 月至 11 月期间韩国一家三甲医院 COVID-19 隔离病房收治的所有标本中含有 CRAB 的 COVID-19 患者:结果:疫情爆发期间,共发现23例COVID-19和CRAB感染患者。感染病例是一名从长期护理机构转来的 85 岁女性。大多数患者(91.3%)的痰培养中都发现了 CRAB。CRAB 的爆发主要发生在病例周围的房间。对房间的地板、进风口、出风口和窗框进行了环境培养。患者和环境中的 CRAB 对抗菌素的耐药性模式完全相同;全基因组测序分析表明其具有分离克隆性。10 月 29 日,医院采取了感染控制措施,使用 1,000 ppm 次氯酸钠和酚类化合物加强环境清洁,加强手部卫生,加强教育,并强制要求患者穿戴 COVID-19 个人防护设备(PPE)。自 11 月 2 日起的两周内未发生 CRAB 感染病例:结论:除了在 COVID-19 隔离病房使用个人防护设备和 COVID-19 预防措施外,坚持严格的接触预防措施和环境控制也有助于防止耐多药细菌的传播。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Carbapenem-resistant Acinetobacter baumannii Outbreak in a COVID-19 Isolation Ward and Successful Outbreak Control with Infection Control Measures.

Background: Even amid the coronavirus disease-19 (COVID-19) pandemic, the spread of multidrug-resistant bacteria and infection control are still important tasks. After recognizing the carbapenem-resistant Acinetobacter baumannii (CRAB) outbreak that occurred in the isolation room for COVID-19, we would like to introduce what infection control measures were implemented to eradicate it.

Materials and methods: All COVID-19 patients with CRAB in any specimen admitted to the COVID-19 isolation ward of the tertiary hospital in Korea from October to November 2021 were analyzed.

Results: During the outbreak, 23 patients with COVID-19 and CRAB infections were identified. The index case was an 85-year-old female referred from a long-term care facility. CRAB was identified in sputum culture in most patients (91.3%). The CRAB outbreak occurred mainly in the rooms around the index case. Environmental cultures on the floor, air inlet, air outlet, and window frame of the rooms were performed. The antimicrobial resistance patterns of CRAB from patients and the environment were identical; whole-genome sequencing analyses revealed isolated clonality. Infection control measures with enhanced environmental cleaning using 1,000 ppm sodium hypochlorite and phenolic compounds, enhanced hand hygiene, additional education, and mandatory additional gowning and gloving of COVID-19 personal protective equipment (PPE) were applied on 29 October. No CRAB infection cases occurred from 2 November for two weeks.

Conclusion: In addition to applying PPE and COVID-19 precautions in COVID-19 isolation wards, adhering to strict contact precautions along with environmental control can help prevent the spread of multidrug-resistant bacteria.

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来源期刊
Infection and Chemotherapy
Infection and Chemotherapy INFECTIOUS DISEASES-
CiteScore
6.60
自引率
11.90%
发文量
71
审稿时长
22 weeks
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