垂体功能减退症和骨病:病理生理学、诊断和治疗效果。

IF 3.3 2区 医学 Q2 ENDOCRINOLOGY & METABOLISM
Amit Akirov, Yaron Rudman, Maria Fleseriu
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引用次数: 0

摘要

垂体功能减退症是一种罕见但严重的内分泌疾病,其特点是一种或多种垂体激素分泌不足。垂体功能减退症与骨骼健康之间错综复杂的关系是医学界日益关注的话题。在这篇综述中,作者探讨了垂体功能减退症与骨骼健康之间的关系,并具体研究了生长激素缺乏症、中枢性性腺功能减退症、中枢性皮质醇功能减退症和中枢性甲状腺功能减退症的影响。作者还讨论了垂体功能减退症的发病机制、诊断和治疗方案,以及骨质疏松、骨质疏松症和骨折所带来的挑战。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Hypopituitarism and bone disease: pathophysiology, diagnosis and treatment outcomes.

Hypopituitarism and bone disease: pathophysiology, diagnosis and treatment outcomes.

Hypopituitarism is a rare but significant endocrine disorder characterized by the inadequate secretion of one or more pituitary hormones. The intricate relationship between hypopituitarism and bone health is a topic of growing interest in the medical community. In this review the authors explore associations between hypopituitarism and bone health, with specific examination of the impact of growth hormone deficiency, central hypogonadism, central hypocortisolism, and central hypothyroidism. Pathogenesis, diagnosis, and treatment options as well as challenges posed by osteopenia, osteoporosis, and fractures in hypopituitarism are discussed.

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来源期刊
Pituitary
Pituitary 医学-内分泌学与代谢
CiteScore
7.10
自引率
7.90%
发文量
90
审稿时长
6 months
期刊介绍: Pituitary is an international publication devoted to basic and clinical aspects of the pituitary gland. It is designed to publish original, high quality research in both basic and pituitary function as well as clinical pituitary disease. The journal considers: Biology of Pituitary Tumors Mechanisms of Pituitary Hormone Secretion Regulation of Pituitary Function Prospective Clinical Studies of Pituitary Disease Critical Basic and Clinical Reviews Pituitary is directed at basic investigators, physiologists, clinical adult and pediatric endocrinologists, neurosurgeons and reproductive endocrinologists interested in the broad field of the pituitary and its disorders. The Editorial Board has been drawn from international experts in basic and clinical endocrinology. The journal offers a rapid turnaround time for review of manuscripts, and the high standard of the journal is maintained by a selective peer-review process which aims to publish only the highest quality manuscripts. Pituitary will foster the publication of creative scholarship as it pertains to the pituitary and will provide a forum for basic scientists and clinicians to publish their high quality pituitary-related work.
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