癌症大手术前的运动能力:关于 6 分钟步行和 30 秒坐立测试有效性的横断面观察研究。

IF 1.4 4区 医学 Q4 ONCOLOGY
Grace Butson, Lara Edbrooke, Hilmy Ismail, Linda Denehy, The Centre for Prehabilitation and Peri-operative Care (CPPOC)
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引用次数: 0

摘要

简介心肺运动测试 (CPET) 是测量运动能力的黄金标准,但它需要大量资源,且可用性有限。本研究旨在确定1)6 分钟步行测试(6MWT)和 30 秒坐立测试(30STS)与 CPET 峰值摄氧量(VO2peak)和无氧阈值(AT)之间的关联;2)与术后并发症风险较高相关的 6MWT 和 30STS 切点:这是一项横断面研究,对一家三级癌症中心在 23 个月内收集的数据进行回顾性分析。测量指标包括 CPET VO2peak 和 AT、6MWT 和 30STS 测试。相关性用于描述变量之间的关系。接收者操作特征曲线分析确定了与 CPET 变量切点一致的 6MWT 和 30STS 切点:结果:共纳入 156 名参与者。6MWT 和 30STS 与 VO2 峰值呈中度相关,rho = 0.65,p = 0.01,rho = 0.52,p 2 峰值 结论:6MWT 和 30STS 与 VO2 峰值均呈中度相关,rho = 0.65,p = 0.01,rho = 0.52,p 2 峰值:在无法进行 CPET 的情况下,6MWT 和 30STS 测试可作为癌症患者术前测量运动能力的替代工具。根据灵敏度和特异性水平确定的一系列 6MWT 和 30STS 切点可用于评估术后结果的风险。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Exercise capacity prior to major cancer surgery: A cross-sectional observational study of the validity of the 6-minute walk and 30-second sit-to-stand tests

Exercise capacity prior to major cancer surgery: A cross-sectional observational study of the validity of the 6-minute walk and 30-second sit-to-stand tests

Introduction

Cardiopulmonary exercise testing (CPET) is the gold standard for measuring exercise capacity, however, it is resource intensive and has limited availability. This study aimed to determine: 1) the association between the 6-min walk test (6MWT) and the 30-s sit-to-stand test (30STS) with CPET peak oxygen uptake (VO2peak) and anaerobic threshold (AT) and 2) 6MWT and 30STS cut points associated with a higher risk of postoperative complications.

Methods

A cross-sectional study, retrospectively analyzing data collected from a tertiary cancer center over a 23-month period. Measures included CPET VO2peak and AT, 6MWT and 30STS test. Correlations were used to characterize relationships between variables. Receiver operating characteristic curve analyses determined 6MWT and 30STS cut points that aligned with CPET variable cut points.

Results

Note that, 156 participants were included. The 6MWT and 30STS displayed moderate correlations with VO2peak, rho = 0.65, p = 0.01 and rho = 0.52, p < 0.005 respectively. Fair correlations were observed between AT and 6MWT (rho = 0.36, p = 0.01) and 30STS (rho = 0.41, p < 0.005). The optimal cut points to identify VO2peak < 15 mL/kg/min were 493.5 m on the 6MWT and 12.5 stands on the 30STS test and for AT < 11 mL/kg/min were 506.5 m on the 6MWT and 12.5 stands on the 30STS test.

Conclusion

Both the 6MWT and 30STS test could be used as alternative tools for measuring exercise capacity preoperatively in the cancer setting where CPET is not available. A range of 6MWT and 30STS cut points, according to sensitivity and specificity levels, may be used to evaluate risk of postoperative outcomes.

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来源期刊
CiteScore
3.40
自引率
0.00%
发文量
175
审稿时长
6-12 weeks
期刊介绍: Asia–Pacific Journal of Clinical Oncology is a multidisciplinary journal of oncology that aims to be a forum for facilitating collaboration and exchanging information on what is happening in different countries of the Asia–Pacific region in relation to cancer treatment and care. The Journal is ideally positioned to receive publications that deal with diversity in cancer behavior, management and outcome related to ethnic, cultural, economic and other differences between populations. In addition to original articles, the Journal publishes reviews, editorials, letters to the Editor and short communications. Case reports are generally not considered for publication, only exceptional papers in which Editors find extraordinary oncological value may be considered for review. The Journal encourages clinical studies, particularly prospectively designed clinical trials.
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