与全肘关节置换术失败相关的预后因素。

IF 4.7 2区 医学 Q2 CELL & TISSUE ENGINEERING
Zaid Hamoodi, Celina K Gehringer, Lucy M Bull, Tom Hughes, Lianne Kearsley-Fleet, Jamie C Sergeant, Adam C Watts
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引用次数: 0

摘要

目的:本研究旨在确定和评估与全肘关节置换术(TEA)失败相关的预后因素的现有文献:使用 MEDLINE、Embase、PubMed 和 Cochrane 进行电子文献检索。纳入了所有报告与初次TEA翻修相关的预后估计因素的研究。采用预后研究质量(QUIPS)工具评估偏倚风险,并采用修改后的建议、评估、发展和评价分级(GRADE)框架评估证据质量。由于证据质量较低且研究性质各异,因此采用了叙事综合法:共有 19 项研究符合纳入标准,调查了 28 个可能的预后因素。大多数 QUIPS 领域(84%)被评为中度至高度偏倚风险。所有预后因素的证据质量都较低或很低。在低质量证据中,在不止一项研究中与 TEA 失败存在一致关联的预后因素有:导致 TEA 的创伤后遗症(无论是单独还是与急性创伤合并)和男性性别。其他几项调查性别的研究报告称两者之间没有关联。有关其他因素的证据质量很低,且大多涉及探索性研究:结论:目前调查与TEA失败相关的预后因素的证据质量较低或很低,研究普遍存在中度到高度的偏倚风险。预后因素具有不确定性,应谨慎解释,临床价值不大。要确定TEA失败的可靠预后因素,需要更高质量的证据。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Prognostic factors associated with failure of total elbow arthroplasty.

Aims: The aims of this study were to identify and evaluate the current literature examining the prognostic factors which are associated with failure of total elbow arthroplasty (TEA).

Methods: Electronic literature searches were conducted using MEDLINE, Embase, PubMed, and Cochrane. All studies reporting prognostic estimates for factors associated with the revision of a primary TEA were included. The risk of bias was assessed using the Quality In Prognosis Studies (QUIPS) tool, and the quality of evidence was assessed using the modified Grading of Recommendations, Assessment, Development, and Evaluations (GRADE) framework. Due to low quality of the evidence and the heterogeneous nature of the studies, a narrative synthesis was used.

Results: A total of 19 studies met the inclusion criteria, investigating 28 possible prognostic factors. Most QUIPS domains (84%) were rated as moderate to high risk of bias. The quality of the evidence was low or very low for all prognostic factors. In low-quality evidence, prognostic factors with consistent associations with failure of TEA in more than one study were: the sequelae of trauma leading to TEA, either independently or combined with acute trauma, and male sex. Several other studies investigating sex reported no association. The evidence for other factors was of very low quality and mostly involved exploratory studies.

Conclusion: The current evidence investigating the prognostic factors associated with failure of TEA is of low or very low quality, and studies generally have a moderate to high risk of bias. Prognostic factors are subject to uncertainty, should be interpreted with caution, and are of little clinical value. Higher-quality evidence is required to determine robust prognostic factors for failure of TEA.

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来源期刊
Bone & Joint Research
Bone & Joint Research CELL & TISSUE ENGINEERING-ORTHOPEDICS
CiteScore
7.40
自引率
23.90%
发文量
156
审稿时长
12 weeks
期刊介绍: The gold open access journal for the musculoskeletal sciences. Included in PubMed and available in PubMed Central.
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