EMM 促进的 Pd 催化固态分子内 Heck 型环化/硼化和铃木偶联：获得功能化吲哚啉

IF 3.6 2区化学 Q1 CHEMISTRY, ORGANIC

Journal of Organic Chemistry Pub Date : 2024-05-06 DOI:10.1021/acs.joc.3c02842

Yuwei Jia, Hui Wang, Jintao Guo, Feng Zhang, Lizhi Zhang, Xinjin Li, Yan Zhao*, Xingliang Bao, Qing Liu*, Xiaowei Li* and Hui Liu*,

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引用次数: 0

摘要

报告了电磁磨（EMM）促进的钯催化固态分子内赫克型环化/硼化和铃木偶联反应。与以往通过交叉耦合反应构建一个化学键的机械化学反应相比，这种策略实现了级联转化和多个化学键的形成。这种转化不需要有机溶剂或额外的加热，而且具有良好的底物范围和较高的官能团耐受性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

EMM-Promoted Pd-Catalyzed Solid State Intramolecular Heck-Type Cyclization/Boronation and Suzuki Couplings: Access to Functionalized Indolines

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EMM-Promoted Pd-Catalyzed Solid State Intramolecular Heck-Type Cyclization/Boronation and Suzuki Couplings: Access to Functionalized Indolines

EMM (electromagnetic mill)-promoted Pd-catalyzed solid state intramolecular Heck-type cyclization/boronation and Suzuki couplings are reported. Compared to previous mechanochemistry that constructed one chemical bond through a cross-coupling reaction, this strategy realizes cascade transformation along with multiple chemical bond formation. This conversion does not require organic solvents or additional heating, and it shows a good substrate scope and high functional group tolerance.

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来源期刊

Journal of Organic Chemistry 化学-有机化学

CiteScore

6.20

自引率

11.10%

发文量

1467

审稿时长

2 months

期刊介绍： Journal of Organic Chemistry welcomes original contributions of fundamental research in all branches of the theory and practice of organic chemistry. In selecting manuscripts for publication, the editors place emphasis on the quality and novelty of the work, as well as the breadth of interest to the organic chemistry community.