MEGA RNA 编辑工具

IF 72.5 1区医学 Q1 ONCOLOGY

Nature Reviews Cancer Pub Date : 2024-05-07 DOI:10.1038/s41568-024-00695-6

Victor Tieu

引用次数: 0

摘要

在这篇 "贸易工具"（Tools of the Trade）文章中，维克多-铁乌（Victor Tieu）介绍了MEGA的开发情况，该平台利用了CRISPR-Cas13d的RNA靶向能力，并展示了如何利用它来提高CAR T细胞的抗肿瘤活性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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A MEGA RNA-editing tool

In this Tools of the Trade article, Victor Tieu describes the development of MEGA, a platform that exploits the RNA-targeting capability of CRISPR–Cas13d and demonstrates its use to improve the anti-tumour activity of CAR T cells.

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来源期刊

Nature Reviews Cancer 医学-肿瘤学

CiteScore

111.90

自引率

0.40%

发文量

审稿时长

6-12 weeks

期刊介绍： Nature Reviews Cancer, a part of the Nature Reviews portfolio of journals, aims to be the premier source of reviews and commentaries for the scientific communities it serves. The correct abbreviation for abstracting and indexing purposes is Nat. Rev. Cancer. The international standard serial numbers (ISSN) for Nature Reviews Cancer are 1474-175X (print) and 1474-1768 (online). Unlike other journals, Nature Reviews Cancer does not have an external editorial board. Instead, all editorial decisions are made by a team of full-time professional editors who are PhD-level scientists. The journal publishes Research Highlights, Comments, Reviews, and Perspectives relevant to cancer researchers, ensuring that the articles reach the widest possible audience due to their broad scope.