肠道微生物群和先天性免疫反应在自身免疫性胰腺炎模型中的作用

IF 1.7 4区医学 Q3 GASTROENTEROLOGY & HEPATOLOGY

Pancreas Pub Date : 2024-05-01 DOI:10.1097/mpa.0000000000002339

Suguru Ito, Masaaki Higashiyama, Hiroyuki Nishimura, Akira Tomioka, Rina Tanemoto, Shin Nishii, Akinori Mizoguchi, Yoshihiro Akita, Yoshikiyo Okada, Chie Kurihara, Kazuyuki Narimatsu, Shunsuke Komoto, Kengo Tomita, Ryota Hokari

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引用次数: 0

摘要

尽管最近有报道称肠道微生物群参与了先天性免疫，但自身免疫性胰腺炎（AIP）的致病性仍不清楚。本研究旨在探讨益生菌是否能通过与先天性免疫的相互作用来改善AIP的炎症。

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The role of gut microbiota and innate immune response in an autoimmune pancreatitis model.

Although the involvement of intestinal microbiota in innate immunity has been reported recently, the pathogenicity of autoimmune pancreatitis (AIP) remains unclear. This study aimed to investigate whether probiotics ameliorate inflammation in AIP through interactions with innate immunity.

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来源期刊

Pancreas 医学-胃肠肝病学

CiteScore

4.70

自引率

3.40%

发文量

289

审稿时长

1 months

期刊介绍： Pancreas provides a central forum for communication of original works involving both basic and clinical research on the exocrine and endocrine pancreas and their interrelationships and consequences in disease states. This multidisciplinary, international journal covers the whole spectrum of basic sciences, etiology, prevention, pathophysiology, diagnosis, and surgical and medical management of pancreatic diseases, including cancer.