用于双相连续流 5-氯甲基糠醛合成的毫米结构盘流逆变器

IF 16.4 1区化学 Q1 CHEMISTRY, MULTIDISCIPLINARY

Accounts of Chemical Research Pub Date : 2024-05-02 DOI:10.1002/cite.202300163

Prof. Dr. Frank Schael, Benjamin Steup, Patrick Rojahn, Prof. Dr. Krishna D. P. Nigam

{"title":"用于双相连续流 5-氯甲基糠醛合成的毫米结构盘流逆变器","authors":"Prof. Dr. Frank Schael, Benjamin Steup, Patrick Rojahn, Prof. Dr. Krishna D. P. Nigam","doi":"10.1002/cite.202300163","DOIUrl":null,"url":null,"abstract":"<p>Syntheses of alternative platform chemicals, such as 5-chloromethylfurfural (CMF), from bio-based starting materials are often associated with complicated kinetic schemes and mass transfer processes. Millistructured flow reactor concepts can help to elucidate kinetic schemes and determine rate constants which are of crucial importance for the design of respective technical processes. For the first time, the influence of proton concentration on the rate constants involved in the biphasic synthesis of CMF is systematically investigated. Results are discussed in terms of green chemistry metrics.</p>","PeriodicalId":1,"journal":{"name":"Accounts of Chemical Research","volume":null,"pages":null},"PeriodicalIF":16.4000,"publicationDate":"2024-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/cite.202300163","citationCount":"0","resultStr":"{\"title\":\"Millistructured Coiled Flow Inverter for Biphasic Continuous Flow 5-Chloromethylfurfural Synthesis\",\"authors\":\"Prof. Dr. Frank Schael, Benjamin Steup, Patrick Rojahn, Prof. Dr. Krishna D. P. Nigam\",\"doi\":\"10.1002/cite.202300163\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p>Syntheses of alternative platform chemicals, such as 5-chloromethylfurfural (CMF), from bio-based starting materials are often associated with complicated kinetic schemes and mass transfer processes. Millistructured flow reactor concepts can help to elucidate kinetic schemes and determine rate constants which are of crucial importance for the design of respective technical processes. For the first time, the influence of proton concentration on the rate constants involved in the biphasic synthesis of CMF is systematically investigated. Results are discussed in terms of green chemistry metrics.</p>\",\"PeriodicalId\":1,\"journal\":{\"name\":\"Accounts of Chemical Research\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":16.4000,\"publicationDate\":\"2024-05-02\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://onlinelibrary.wiley.com/doi/epdf/10.1002/cite.202300163\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Accounts of Chemical Research\",\"FirstCategoryId\":\"5\",\"ListUrlMain\":\"https://onlinelibrary.wiley.com/doi/10.1002/cite.202300163\",\"RegionNum\":1,\"RegionCategory\":\"化学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"CHEMISTRY, MULTIDISCIPLINARY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Accounts of Chemical Research","FirstCategoryId":"5","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.1002/cite.202300163","RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"CHEMISTRY, MULTIDISCIPLINARY","Score":null,"Total":0}

引用次数: 0

摘要

从生物基起始材料合成 5-氯甲基糠醛（CMF）等替代平台化学品通常涉及复杂的动力学方案和传质过程。毫微结构流动反应器概念有助于阐明动力学方案和确定速率常数，这对设计相应的技术工艺至关重要。本文首次系统地研究了质子浓度对双相合成 CMF 的速率常数的影响。研究结果将根据绿色化学指标进行讨论。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

Millistructured Coiled Flow Inverter for Biphasic Continuous Flow 5-Chloromethylfurfural Synthesis

查看原文本刊更多论文

Millistructured Coiled Flow Inverter for Biphasic Continuous Flow 5-Chloromethylfurfural Synthesis

Syntheses of alternative platform chemicals, such as 5-chloromethylfurfural (CMF), from bio-based starting materials are often associated with complicated kinetic schemes and mass transfer processes. Millistructured flow reactor concepts can help to elucidate kinetic schemes and determine rate constants which are of crucial importance for the design of respective technical processes. For the first time, the influence of proton concentration on the rate constants involved in the biphasic synthesis of CMF is systematically investigated. Results are discussed in terms of green chemistry metrics.

求助全文

通过发布文献求助，成功后即可免费获取论文全文。去求助

来源期刊

Accounts of Chemical Research 化学-化学综合

CiteScore

31.40

自引率

1.10%

发文量

312

审稿时长

2 months

期刊介绍： Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.