室性心律失常的放射治疗

IF 2.2 4区医学 Q2 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING

Journal of Medical Imaging and Radiation Oncology Pub Date : 2024-05-03 DOI:10.1111/1754-9485.13662

Xingzhou Liulu, Poornima Balaji, Jeffrey Barber, Kasun De Silva, Tiarne Murray, Andrew Hickey, Timothy Campbell, Jill Harris, Harriet Gee, Verity Ahern, Saurabh Kumar, Eric Hau, Pierre C Qian

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引用次数: 0

摘要

室性心律失常（VA）是一种危及生命的心律失常，可导致严重的发病率和死亡率。导管消融术（CA）是一种侵入性治疗方式，在药物治疗无效的情况下可有效治疗室性心律失常。导管消融术后复发的情况很常见，这是因为无法提供足够深度的病灶以烧灼驱动室上性心律失常的电路，或无法到达导致室上性心律失常的瘢痕区域。立体定向体放射治疗是一种非侵入性治疗方式，可通过容积式能量传输治疗 CA 无法到达的电路。它克服了CA的弱点，并已在小型临床试验中成功用于治疗难治性VA。本文总结了这种新型治疗模式的现有证据，以及将其推向 VA 治疗前沿所需的步骤。

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Radiation therapy for ventricular arrhythmias

Ventricular arrhythmias (VA) can be life‐threatening arrhythmias that result in significant morbidity and mortality. Catheter ablation (CA) is an invasive treatment modality that can be effective in the treatment of VA where medications fail. Recurrence occurs commonly following CA due to an inability to deliver lesions of adequate depth to cauterise the electrical circuits that drive VA or reach areas of scar responsible for VA. Stereotactic body radiotherapy is a non‐invasive treatment modality that allows volumetric delivery of energy to treat circuits that cannot be reached by CA. It overcomes the weaknesses of CA and has been successfully utilised in small clinical trials to treat refractory VA. This article summarises the current evidence for this novel treatment modality and the steps that will be required to bring it to the forefront of VA treatment.

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来源期刊

Journal of Medical Imaging and Radiation Oncology 医学-核医学

CiteScore

3.30

自引率

6.20%

发文量

133

审稿时长

6-12 weeks

期刊介绍： Journal of Medical Imaging and Radiation Oncology (formerly Australasian Radiology) is the official journal of The Royal Australian and New Zealand College of Radiologists, publishing articles of scientific excellence in radiology and radiation oncology. Manuscripts are judged on the basis of their contribution of original data and ideas or interpretation. All articles are peer reviewed.