粒子疗法的技术发展与未来展望:专题回顾

IF 4.6 Q1 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING
Aafke Christine Kraan;Alberto Del Guerra
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引用次数: 0

摘要

过去几十年来,在提高粒子治疗质量和效率方面取得了重要的技术进步。剂量投放、治疗计划和验证技术的不断改进,使得剂量符合性更高,并能更好地保护健康组织。与此同时,粒子治疗比传统放疗复杂且昂贵得多,只有高度专业化的设施才能提供这种治疗。因此,降低成本是该领域技术发展的强大动力。在过去的几十年里,提供质子和碳治疗的治疗机构数量急剧增加,研究工作和创新也不断增多。从技术角度看,硬件的进步往往伴随着软件和计算的创新,反之亦然。在这篇综述中,我们将对粒子治疗硬件(加速器、龙门架、超导应用、治疗验证技术)、软件(蒙特卡罗模拟、治疗规划计算)以及临床应用研究方面的技术进步进行基本概述。通过将广泛的选题整合到一篇综述中,并同时涵盖质子治疗和碳治疗,我们旨在为读者提供有关粒子治疗各种技术发展的独特概览。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Technological Developments and Future Perspectives in Particle Therapy: A Topical Review
In the last decades, important technological progress has been made to enhance the quality and efficiency of particle therapy treatments. Continuous improvements in dose delivery, treatment planning and verification techniques have led to higher-dose conformity and better sparing of healthy tissue. At the same time, particle therapy treatments are complex and much more expensive than conventional radiotherapy, and only highly specialized facilities can offer these treatments. Cost reduction is thus a strong drive behind technological developments in the field. The number of treatment facilities offering proton and carbon therapy has strongly grown in the last decades, and the amount of research efforts and innovations have increased continuously. From a technological perspective, advances in hardware are often accompanied by innovations in software and computation, and vice versa. In this review we will present a basic overview of technological advances in particle therapy hardware (accelerators, gantries, applications of superconductivity, treatment verification techniques), software (Monte Carlo simulations, treatment planning calculations), and studies toward clinical applications. By combining a broad selection of topics into a single review and by covering both proton and carbon therapy, we aim at providing the reader a unique overview of the evolution of various technologies developed for particle therapy.
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来源期刊
IEEE Transactions on Radiation and Plasma Medical Sciences
IEEE Transactions on Radiation and Plasma Medical Sciences RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING-
CiteScore
8.00
自引率
18.20%
发文量
109
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