揭开与人类疾病相关的波形蛋白丝结构的秘密

IF 12.5 1区生物学 Q1 BIOCHEMISTRY & MOLECULAR BIOLOGY

Nature Structural & Molecular Biology Pub Date : 2024-04-29 DOI:10.1038/s41594-024-01301-x

Ivan B. Lomakin, Minh Ho, Christopher G. Bunick

引用次数: 0

摘要

人类细胞骨架由三大类丝组成：微丝、微管和中间丝。在此，我们总结了在破译中间丝的结构和功能及其对人类疾病的影响方面取得的最新进展。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

Unveiling the secrets of vimentin filament architecture relevant to human disease

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Unveiling the secrets of vimentin filament architecture relevant to human disease

The human cytoskeleton consists of three major classes of filaments: microfilaments, microtubules and intermediate filaments. Here, we summarize recent progress in deciphering the structure and function of intermediate filaments and their implications for human disease.

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来源期刊

Nature Structural & Molecular Biology BIOCHEMISTRY & MOLECULAR BIOLOGY-BIOPHYSICS

CiteScore

22.00

自引率

1.80%

发文量

160

审稿时长

3-8 weeks

期刊介绍： Nature Structural & Molecular Biology is a comprehensive platform that combines structural and molecular research. Our journal focuses on exploring the functional and mechanistic aspects of biological processes, emphasizing how molecular components collaborate to achieve a particular function. While structural data can shed light on these insights, our publication does not require them as a prerequisite.