脊髓损伤成人的肌肉骨骼发病率：全国性队列研究

IF 16.4 1区化学 Q1 CHEMISTRY, MULTIDISCIPLINARY

Accounts of Chemical Research Pub Date : 2024-04-26 DOI:10.3233/nre-230263

Youngoh Bae, Hohyun Jung, Nakyung Shin, Masoud Rahmati, Raphael Udeh, Abdolreza Kazemi, Yusheng Li, Marco Solmi, Muhammad Syafrudin, Norma Latif Fitriyani, Guillaume Fond, Laurent Boyer, Seung Won Lee

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引用次数: 0

摘要

背景：脊髓损伤（SCI）后，人们对生活质量要求的提高与肌肉骨骼（MSK）疼痛的增加有关，这凸显了预防措施研究的必要性。目的：本研究旨在评估韩国脊髓损伤成人 MSK 疾病的发病率和危害性，以及脊髓损伤位置对 MSK 疾病的影响。方法：从韩国国民健康保险服务数据（n = 276）中选取患者群体。对照组包括无 SCI 的个体（n = 10,000）。我们比较了常见 MSK 疾病（骨关节炎、结缔组织疾病、肌肉疏松症、肌痛、神经痛、类风湿性关节炎、肌炎和肌肉骨骼感染）的发病率，并根据受伤部位（颈椎、胸椎或腰椎）确定了未经调整和调整的危险比（HRs）。结果：与无 SCI 的人相比，有 SCI 的成年人 MSK 发病率更高（48.45% 对 36.6%），存活概率更低。颈部脊髓损伤的 MSK 发病率和存活概率没有显著差异，而胸椎和腰椎损伤的 MSK 发病率和存活概率则有显著差异。结论：脊髓损伤会增加多发性硬化症的发病风险。与颈椎或胸椎 SCI 相比，腰椎 SCI 的发病率和 MSK 发病风险更高。

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Musculoskeletal morbidity in adults with spinal cord injuries: A nationwide cohort study

BACKGROUND:An increase in the demand for quality of life following spinal cord injuries (SCIs) is associated with an increase in musculoskeletal (MSK) pain, highlighting the need for preventive measure research. OBJECTIVE:This study aimed to evaluate the incidence and hazards of MSK morbidities among Korean adults with SCIs, as well as the influence of SCI location on MSK morbidities. METHODS:Patient populations were selected from Korean National Health Insurance Service data (n = 276). The control group included individuals without SCIs (n = 10,000). We compared the incidences and determined the unadjusted and adjusted hazard ratios (HRs) of common MSK morbidities (osteoarthritis, connective tissue disorders, sarcopenia, myalgia, neuralgia, rheumatoid arthritis, myositis, and musculoskeletal infections) based on the location of injury (cervical, thoracic, or lumbar). RESULTS:Adults with SCIs had a higher incidence of MSK morbidity (48.45% vs. 36.6%) and a lower survival probability than those without SCIs. The incidence of MSK morbidity and survival probabilities were not significantly different for cervical cord injuries, whereas both measures were significantly different for thoracic and lumbar injuries. CONCLUSION:SCI increases the risk of MSK morbidity. Lumbar SCI is associated with a higher incidence and risk of MSK morbidity than are cervical or thoracic SCIs.

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来源期刊

Accounts of Chemical Research 化学-化学综合

CiteScore

31.40

自引率

1.10%

发文量

312

审稿时长

2 months

期刊介绍： Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.