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引用次数: 0
摘要
自 COVID-19 大流行开始以来,人们越来越清楚地认识到,这种疾病可能会产生相关的多系统和长期影响,一些研究也试图找出决定疾病进程的关键因素。在此,我们讨论了最近的一些证据,这些证据表明,在长期感染 COVID 的患者中,与这两种营养素水平正常的患者相比,同时缺乏镁和维生素 D 的患者会出现更多的临床表现。我们强调了这些营养素缺乏可能产生的协同效应,并建议未来的研究应探讨与罹患长COVID风险之间的因果关系。最重要的是,我们需要进行随机临床试验,以确定镁和维生素 D 补充剂是否能改善长期 COVID 症状,从而提供一种安全且负担得起的支持疗法,造福患者和社会。
Magnesium and vitamin D in long COVID syndrome; do they help?
Since the start of the COVID-19 pandemic, it has become increasingly clear that the disease can have relevant multisystemic and long-term effects, and several studies have attempted to identify key determinants of the disease course. Here we discuss recent evidence suggesting that, in long COVID patients, combined magnesium and vitamin D deficiencies associate with a higher number of clinical manifestations, as compared to patients with normal levels of both nutrients. We highlight the potential synergistic effects of these deficiencies and propose that future studies should explore a causal link with the risk of developing long COVID. Most importantly, randomized clinical trials are needed to determine if magnesium and vitamin D supplementation can improve long COVID symptoms, providing a safe and affordable support therapy to the benefit of patients and society.
期刊介绍:
Magnesium Research, the official journal of the international Society for the Development of Research on Magnesium (SDRM), has been the benchmark journal on the use of magnesium in biomedicine for more than 30 years.
This quarterly publication provides regular updates on multinational and multidisciplinary research into magnesium, bringing together original experimental and clinical articles, correspondence, Letters to the Editor, comments on latest news, general features, summaries of relevant articles from other journals, and reports and statements from national and international conferences and symposiums.
Indexed in the leading medical databases, Magnesium Research is an essential journal for specialists and general practitioners, for basic and clinical researchers, for practising doctors and academics.