Nanoliposome: As a smart nanocarrier in transdermal drug delivery system

In the current advancement of drug delivery systems, nanoliposome vesicles act as a modernized technology for the encapsulation of bioactive agents. The prerequisite to expand biocompatible, structured, patient compliance, and guarded treatments in the biomedical sector is gaining distinctive recognition for employing the field of nanotechnology as capable medium to design new drug delivery systems. The liberty of this review is to initiate the concept of nanoliposomes and also elaborate on a few facets and mechanisms of nanoliposomes at the transdermal site. The enormous list of bioactive materials can be incorporated into nanoliposomes, ranging from the pharmaceuticals and cosmetics industry. The prototypical liposomes have inadequate possibility as a carrier for drug delivery via the skin because they do not penetrate the deeper layer of the skin. Only designed liposomes have the capacity to achieve enhanced delivery. It has unusual properties like biodegradability, biocompatibility, and nano size. The exclusive characteristics of nanoliposomes are their ability to solubilize and sectionalize both hydrophilic and hydrophobic bioactive agents. It intensifies the performance of bioactive agent by enhancing their solubility and bioavailability. High-quality phospholipids, the cornerstone of nanoliposomal lipid bilayer are the key components. This review article intends to provide an overview of liposomes and nanoliposomes their properties, preparation methods, and evaluation parameters. Also, it explains various applications of nanoliposomes in nanotherapy including diagnostics, specifically cancer, cosmetics, and nutraceuticals.