双鲁单抗替代皮质类固醇治疗过敏性支气管肺曲霉病加重期的疗效

IF 0.8 Q4 RESPIRATORY SYSTEM

Respirology Case Reports Pub Date : 2024-04-01 DOI:10.1002/rcr2.1354

Masamitsu Hamakawa, Tadashi Ishida

引用次数: 0

摘要

关键信息过敏性支气管肺曲霉病的发病机制不仅涉及嗜酸性粒细胞，还涉及产生免疫球蛋白E的浆细胞。Dupilumab通过阻断IL4抑制T细胞向浆细胞分化，因此可能是皮质类固醇的有效替代品。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

查看原文本刊更多论文

Efficacy of dupilumab as an alternative to corticosteroids in the treatment of exacerbations of allergic bronchopulmonary aspergillosis

Key message The pathogenesis of allergic bronchopulmonary aspergillosis involves not only eosinophils but also plasma cells that produce immunoglobulin E. Dupilumab may be an effective alternative to corticosteroids because it inhibits T cell to plasma cell differentiation by blocking IL4.

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来源期刊

Respirology Case Reports RESPIRATORY SYSTEM-

CiteScore

1.40

自引率

0.00%

发文量

178

审稿时长

8 weeks

期刊介绍： Respirology Case Reports is an open-access online journal dedicated to the publication of original clinical case reports, case series, clinical images and clinical videos in all fields of respiratory medicine. The Journal encourages the international exchange between clinicians and researchers of experiences in diagnosing and treating uncommon diseases or diseases with unusual presentations. All manuscripts are peer-reviewed through a streamlined process that aims at providing a rapid turnaround time from submission to publication.