用 Ponseti 技术矫正马蹄内翻足:三维对齐分析和残余成人畸形对患者报告结果的影响

Ryan Jasper, K. Carvalho, Aly M. Fayed, Antoine Acker, Vineel Mallavarapu, Grayson M. Talaski, N. Mansur, Bopha Chrea, C. de César Netto
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Every participant was evaluated using a WBCT (HiRise©) in a bipedal standing position. From these scans Cavus, Adductus, and Varus components were evaluated using multiple 3D measurements calculated using the semi-automatic segmentation software Bonelogic®. Specific Cavus related measurements included sagittal talus-first metatarsal angle and the calcaneal inclination angle. Varus related measurements included talocalcaneal angle in both the sagittal and axial planes as well as the hindfoot moment arm and the hindfoot alignment angle. Adductus deformity was evaluated using talonavicular coverage angle. These measurements were then correlated with patient reported outcome surveys, which included Visual Acuity Scale for pain, PROMIS general health, PROMIS physical function, PROMIS pain interference, pain catastrophic scale, and European foot and ankle society score. 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引用次数: 0

摘要

引言/目的:很少有研究对 Ponseti 技术的长期疗效进行评估,也没有研究利用三维负重分析。本研究的目的是了解潜在的残余三维畸形和异常如何影响患者报告结果(PROs)。为此,研究人员使用三维负重 CT (WBCT) 成像评估了接受 Ponseti 方法治疗的成人马蹄内翻足患者的足部和踝部解剖对齐情况,然后将残留的足部和踝部对齐不良情况与患者报告结果进行了关联分析。方法:本研究共纳入 37 名连续患者(57 只脚)和 14 名健康对照志愿者(28 只脚)。每位参与者都在双足站立姿势下使用 WBCT(HiRise©)进行了评估。通过使用半自动分割软件 Bonelogic® 计算出的多个三维测量值,对这些扫描结果中的腔隙、内收和外翻成分进行评估。与Cavus相关的具体测量包括距骨-第一跖骨矢状角和小关节倾斜角。与Varus相关的测量包括矢状面和轴向的距骨-髋臼角以及后足力矩臂和后足对齐角。内收畸形通过距骨覆盖角进行评估。然后将这些测量结果与患者报告结果调查相关联,其中包括疼痛视觉敏锐度量表、PROMIS 一般健康状况、PROMIS 身体功能、PROMIS 疼痛干扰、疼痛灾难量表以及欧洲足踝协会评分。结果显示与对照组相比,马蹄内翻足患者没有观察到明显的整体残余三维畸形,两组间的 FAO 测量值相似,马蹄内翻足=2.63%(95%CI=1.41%-3.85%),对照组=3.2%(CI=1.6%- 4.8%,P=0.58)。与对照组的-5.2°相比,足外翻患者距骨-第一跖骨矢状面的平均值为-0.12°。与对照组相比,足外翻患者的小关节倾角也有所减小,分别为13.01°和21.5°。与对照组相比,足外翻患者在矢状面(44.28°)和轴向面(17.74°)上的足髁角都有所减小,分别为 57.51°和 25.78°。足外翻组的距骨覆盖角(18.63°)小于对照组(29.19°)。矢状面上的距骨-第一跖骨-角度与 VAS 评分(RSquare=0.19,P=0.0118)和 EFAS 评分(RSquare=0.27,P=0.0025)显著相关。矢状面上的踝关节角度也与 PROMIS 疼痛干扰评分(P=0.038)和 PROMIS 物理功能评分(RSquare=0.32,P=0.0007)显著相关。结论Ponseti 技术是一种有效的非手术疗法,可帮助马蹄内翻足患者实现足部和踝部的整体三维对齐。虽然在成年足外翻患者中观察到轻度但有统计学意义的残余Varus和Adductus畸形,但发现足外翻患者和对照组的整体三维对齐(FAO)相似。这些发现凸显了 Ponseti 技术的疗效,也可能解释了为何患者的 PROs 总体良好。这项研究的结果有可能为今后治疗马蹄内翻足患儿提供治疗目标,帮助优化患者的治疗效果。Ponseti技术是一种有效的非手术治疗方法,可改善马蹄内翻足患者足部和踝关节的整体三维排列。虽然在成人马蹄内翻足患者中观察到了轻微但具有统计学意义的残余Varus和Adductus畸形,但发现马蹄内翻足患者和对照组之间的整体三维排列(FAO)相似。这些发现凸显了 Ponseti 技术的疗效,也可能解释了为何患者的 PROs 总体良好。这项研究的结果有可能为今后治疗儿童足外翻患者提供治疗目标,帮助优化患者的治疗效果。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Clubfoot Correction with Ponseti Technique: Three-Dimensional Alignment Analysis and Residual Adult Deformity Effects on Patient-Reported Outcomes
Introduction/Purpose: Few studies have assessed the long-term outcomes of the Ponseti technique and none have utilized 3- dimensional weightbearing analysis. The goal of this study was to understand how potential residual 3D deformities and abnormalities influence patient reported outcomes (PROs). This was accomplished by assessing anatomical foot and ankle alignment in adult clubfoot patients treated with the Ponseti method using 3D weightbearing CT (WBCT) imaging and then correlating residual foot and ankle malalignment with PROs. Methods: There were 37 consecutive patients (57 feet) included and 14 volunteers healthy controls (28 feet) included in this study. Every participant was evaluated using a WBCT (HiRise©) in a bipedal standing position. From these scans Cavus, Adductus, and Varus components were evaluated using multiple 3D measurements calculated using the semi-automatic segmentation software Bonelogic®. Specific Cavus related measurements included sagittal talus-first metatarsal angle and the calcaneal inclination angle. Varus related measurements included talocalcaneal angle in both the sagittal and axial planes as well as the hindfoot moment arm and the hindfoot alignment angle. Adductus deformity was evaluated using talonavicular coverage angle. These measurements were then correlated with patient reported outcome surveys, which included Visual Acuity Scale for pain, PROMIS general health, PROMIS physical function, PROMIS pain interference, pain catastrophic scale, and European foot and ankle society score. Results: There was no significant overall residual 3D-deformity observed in clubfoot patients when compared to controls, with similar FAO measurements observed between the groups, clubfoot=2.63% (95%CI=1.41%-3.85%) and control=3.2% (CI=1.6%- 4.8%,P=0.58). The sagittal talus-first-metatarsal in the clubfoot-patients had a mean-value of -0.12° compared to the controls, −5.2°. Clubfoot patients also had a decreased calcaneal-inclination-angle relative to the controls, 13.01° and 21.5° respectively. Talocalcaneal-angle for clubfoot patients in both the sagittal-plane,44.28°, and axial-plane, 17.74°, were reduced compared to the controls, 57.51° and 25.78°. Talonavicular-coverage-angle in the clubfoot-group (18.63°) was less than the controls (29.19°). Talus- first-metatarsal-angle in the sagittal-plane was significantly correlated with VAS-scores (RSquare=0.19,P=0.0118) and the EFAS- Score (RSquare=0.27,P=0.0025). Talocalcaneal-angle in the sagittal plane was also significantly correlated with the PROMIS-Pain- Interference-score (P=0.038) and PROMIS-Physical-Function-score (RSquare=0.32,P=0.0007). Conclusion: The Ponseti technique is an effective nonsurgical treatment for the overall three-dimensional foot and ankle alignment of Clubfoot. While mild, but statistically significant residual Varus and Adductus deformities were observed in adult clubfoot patients, the overall 3D alignment (FAO) was found to be similar between clubfoot patients and controls. These findings highlight the efficacy of the Ponseti technique and potentially explain the overall good PROs. The results of this study could potentially provide insight into treatment targets that may be applied to help optimize patient outcomes when treating children with Clubfoot in the future. The Ponseti technique is an effective nonsurgical treatment for Clubfoot's overall three-dimensional foot and ankle alignment. While mild, but statistically significant residual Varus and Adductus deformities were observed in adult clubfoot patients, the overall 3D alignment (FAO) was found to be similar between clubfoot patients and controls. These findings highlight the efficacy of the Ponseti technique and potentially explain the overall good PROs. The results of this study could potentially provide insight into treatment targets that may be applied to help optimize patient outcomes when treating children with Clubfoot in the future.
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来源期刊
Foot & Ankle Orthopaedics
Foot & Ankle Orthopaedics Medicine-Orthopedics and Sports Medicine
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