L. P. Maskin, S. E. Noya, G. Caffaratti, María Martina Echarri, Alejandro F Hlavnicka, A. Cervio
{"title":"腰部导管对内窥镜鼻内入路手术后脑膜炎发生率的影响","authors":"L. P. Maskin, S. E. Noya, G. Caffaratti, María Martina Echarri, Alejandro F Hlavnicka, A. Cervio","doi":"10.1055/a-2298-0898","DOIUrl":null,"url":null,"abstract":"Objectives: Endoscopic endonasal approach (EEA) procedures are inherently contaminated due to direct access through the nasopharyngeal mucosa. The reported rate of postoperative meningitis in EEA procedures is between 0.7%-10%. Lumbar catheters are used in EEA surgeries to prevent cerebrospinal fluid (CSF) fistulae, but its use is associated with increase infection rates. This study investigated whether there is a difference in rates of postoperative meningitis based on lumbar catheter utilization. \nMethods: We performed a retrospective review of consecutive patients who underwent EEA surgeries between January 2016 and March 2023 at single-institution (FLENI). \nMain outcome: Incidence of meningitis following EEA surgery with lumbar catheter.\nResults: seventy-two patients were enrolled, median age was 44 years, and 53% were female. Most frequent surgery performed was craniopharyngioma 46% (26 patients). Lumbar catheter was used in twenty-eight patients. Meningitis was diagnosis in 11 of 72 patients (15.2%), being higher in the lumbar catheter group (10 patients). The odds ratio for the development of meningitis in the presence of a lumbar catheter was 23.38 (95% confidence interval, 2.77-123.78; p < 0.004). There was no statistical difference in reported incidence of meningitis when CSF leak was present. \nConclusions: This study demonstrates an extremely high incidence of meningitis (36%) following EEA procedures when lumbar catheter is used. The incidence of meningitis was not significantly associated with CSF leak in our cohort.\n","PeriodicalId":16513,"journal":{"name":"Journal of Neurological Surgery Part B: Skull Base","volume":null,"pages":null},"PeriodicalIF":0.9000,"publicationDate":"2024-04-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Impact of the lumbar catheter on the incidence of post-surgical meningitis in the endoscopic endonasal approach\",\"authors\":\"L. P. Maskin, S. E. Noya, G. Caffaratti, María Martina Echarri, Alejandro F Hlavnicka, A. Cervio\",\"doi\":\"10.1055/a-2298-0898\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Objectives: Endoscopic endonasal approach (EEA) procedures are inherently contaminated due to direct access through the nasopharyngeal mucosa. The reported rate of postoperative meningitis in EEA procedures is between 0.7%-10%. Lumbar catheters are used in EEA surgeries to prevent cerebrospinal fluid (CSF) fistulae, but its use is associated with increase infection rates. This study investigated whether there is a difference in rates of postoperative meningitis based on lumbar catheter utilization. \\nMethods: We performed a retrospective review of consecutive patients who underwent EEA surgeries between January 2016 and March 2023 at single-institution (FLENI). \\nMain outcome: Incidence of meningitis following EEA surgery with lumbar catheter.\\nResults: seventy-two patients were enrolled, median age was 44 years, and 53% were female. Most frequent surgery performed was craniopharyngioma 46% (26 patients). Lumbar catheter was used in twenty-eight patients. Meningitis was diagnosis in 11 of 72 patients (15.2%), being higher in the lumbar catheter group (10 patients). The odds ratio for the development of meningitis in the presence of a lumbar catheter was 23.38 (95% confidence interval, 2.77-123.78; p < 0.004). There was no statistical difference in reported incidence of meningitis when CSF leak was present. \\nConclusions: This study demonstrates an extremely high incidence of meningitis (36%) following EEA procedures when lumbar catheter is used. The incidence of meningitis was not significantly associated with CSF leak in our cohort.\\n\",\"PeriodicalId\":16513,\"journal\":{\"name\":\"Journal of Neurological Surgery Part B: Skull Base\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.9000,\"publicationDate\":\"2024-04-02\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Neurological Surgery Part B: Skull Base\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1055/a-2298-0898\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"Medicine\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Neurological Surgery Part B: Skull Base","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1055/a-2298-0898","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"Medicine","Score":null,"Total":0}
Impact of the lumbar catheter on the incidence of post-surgical meningitis in the endoscopic endonasal approach
Objectives: Endoscopic endonasal approach (EEA) procedures are inherently contaminated due to direct access through the nasopharyngeal mucosa. The reported rate of postoperative meningitis in EEA procedures is between 0.7%-10%. Lumbar catheters are used in EEA surgeries to prevent cerebrospinal fluid (CSF) fistulae, but its use is associated with increase infection rates. This study investigated whether there is a difference in rates of postoperative meningitis based on lumbar catheter utilization.
Methods: We performed a retrospective review of consecutive patients who underwent EEA surgeries between January 2016 and March 2023 at single-institution (FLENI).
Main outcome: Incidence of meningitis following EEA surgery with lumbar catheter.
Results: seventy-two patients were enrolled, median age was 44 years, and 53% were female. Most frequent surgery performed was craniopharyngioma 46% (26 patients). Lumbar catheter was used in twenty-eight patients. Meningitis was diagnosis in 11 of 72 patients (15.2%), being higher in the lumbar catheter group (10 patients). The odds ratio for the development of meningitis in the presence of a lumbar catheter was 23.38 (95% confidence interval, 2.77-123.78; p < 0.004). There was no statistical difference in reported incidence of meningitis when CSF leak was present.
Conclusions: This study demonstrates an extremely high incidence of meningitis (36%) following EEA procedures when lumbar catheter is used. The incidence of meningitis was not significantly associated with CSF leak in our cohort.
期刊介绍:
The Journal of Neurological Surgery Part B: Skull Base (JNLS B) is a major publication from the world''s leading publisher in neurosurgery. JNLS B currently serves as the official organ of several national and international neurosurgery and skull base societies.
JNLS B is a peer-reviewed journal publishing original research, review articles, and technical notes covering all aspects of neurological surgery. The focus of JNLS B includes microsurgery as well as the latest minimally invasive techniques, such as stereotactic-guided surgery, endoscopy, and endovascular procedures. JNLS B is devoted to the techniques and procedures of skull base surgery.