系统性硬化症患者在 COVID-19 期间的体育活动:以硬皮病患者为中心的干预网络 COVID-19 队列纵向研究

IF 16.4 1区 化学 Q1 CHEMISTRY, MULTIDISCIPLINARY
Amanda Wurz, Richard S Henry, L. Kwakkenbos, M. Carrier, Scott B. Patten, Susan J Bartlett, L. Mouthon, John Varga, Andrea Benedetti, S. Culos-Reed, Brett D. Thombs
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引用次数: 0

摘要

系统性硬化症(SSc)患者在体育锻炼方面面临障碍。很少有研究描述过系统性硬化症患者的体育锻炼情况,也没有研究对 COVID-19 期间的体育锻炼情况进行纵向调查。我们评估了 2020 年 4 月至 2022 年 3 月期间 SSc 患者的体育锻炼情况。以硬皮病患者为中心的干预网络(SPIN)COVID-19 队列于 2020 年 4 月启动,包括正在进行的 SPIN 队列的参与者和外部参与者。参与者在 2020 年 7 月之前每两周完成一次测量,之后每 4 周完成一次测量(28 次评估)。体力活动通过自我报告的国际老年人体力活动问卷进行评估。分析包括各次评估中体力活动的估计平均值和 95% 的置信区间。主要分析对缺失数据进行了估算。敏感性分析包括仅评估在 28 项可能评估中完成 21 项以上评估项目且完成率大于 90% 的参与者("完成者"),并按性别、年龄、国家和 SSc 亚型进行分层分析。共有 800 名 SSc 患者参加了这项研究。平均年龄为 55.6 岁(标准差 (SD) = 12.6)。2020 年 4 月至 2021 年 3 月期间,体育锻炼量明显减少(标准化平均差 (SMD) = -0.17,95% 置信区间 (CI) = -0.26 至 -0.07),2021 年 3 月至 2022 年 3 月期间,体育锻炼量保持稳定(SMD = -0.05,95% CI = -0.15 至 0.05)。完成者和亚组的结果相似。在各次评估中,达到世界卫生组织推荐的每周至少 150 分钟中度到剧烈运动的最低运动量的参与者比例从 63% 到 82% 不等。在整个大流行期间,体力活动的平均下降幅度相对较小。大多数参与者都达到了建议的体育锻炼水平。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Physical activity during COVID-19 in people with systemic sclerosis: A Scleroderma Patient-centred Intervention Network COVID-19 Cohort longitudinal study
People with systemic sclerosis (SSc) face barriers to physical activity. Few studies have described physical activity in SSc, and none have explored physical activity longitudinally during COVID-19. We evaluated physical activity from April 2020 to March 2022 among people with SSc. The Scleroderma Patient-centred Intervention Network (SPIN) COVID-19 Cohort was launched in April 2020 and included participants from the ongoing SPIN Cohort plus external enrolees. Participants completed measures bi-weekly through July 2020, then every 4 weeks afterwards (28 assessments). Physical activity was assessed via the self-reported International Physical Activity Questionnaire-Elderly. Analyses included estimated means with 95% confidence intervals for physical activity across assessments. Missing data were imputed for main analyses. Sensitivity analyses included evaluating only participants who completed >90% of items for >21 of 28 possible assessments (‘completers’) and stratified analyses by sex, age, country and SSc subtype. A total of 800 people with SSc enrolled. Mean age was 55.6 (standard deviation (SD) = 12.6) years. Physical activity significantly decreased from April 2020 to March 2021 (standardized mean difference (SMD) = −0.17, 95% confidence interval (CI) = −0.26 to −0.07) and was stable from March 2021 to March 2022 (SMD = −0.05, 95% CI = −0.15 to 0.05). Results were similar for completers and subgroups. The proportion of participants who met World Health Organization minimum physical activity recommendations of at least 150 min of moderate-to-vigorous activity per week ranged from 63% to 82% across assessments. Physical activity decreased by a relatively small amount, on average, across the pandemic. Most participants met recommended physical activity levels.
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来源期刊
Accounts of Chemical Research
Accounts of Chemical Research 化学-化学综合
CiteScore
31.40
自引率
1.10%
发文量
312
审稿时长
2 months
期刊介绍: Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.
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