利妥昔单抗治疗后的爆发性痣:不寻常的皮肤镜表现:病例报告

Ghita Sqalli Houssini
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摘要

背景:爆发痣可在各种情况下发生,包括使用生物制剂等免疫抑制和免疫调节药物。皮肤镜检查通常会发现外围呈环状排列的棕色小球。我们报告了一例接受利妥昔单抗治疗的患者皮肤镜下形态不典型的爆发痣病例。观察结果一名 37 岁的女性患者因获得性大疱性表皮松解症接受随访,6 个月后出现色素沉着和广泛的斑丘疹。皮肤镜检查发现,患者躯干上的皮损面积不断增大,皮损呈均匀的棕色,中心和周边有不规则排列的棕色小球和小点。活组织检查显示这是一个交界痣。结论首次描述了皮肤镜检查下爆发痣的非典型棕色模式,尤其是在利妥昔单抗治疗后。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Eruptive Nevus Following Rituximab Treatment: Unusual Dermoscopic Presentation: A Case Report
Background: Eruptive nevi can occur following various conditions, including the use of immunosuppressive and immunomodulatory drugs such as biologics. Dermoscopy typically reveals a pattern of brown globules arranged in a ring at the periphery. We report a case of eruptive nevus with an atypical dermoscopic pattern in a patient receiving Rituximab. Observation: A 37-year-old female patient, followed for acquired bullous epidermolysis, developed pigmented and extensive macules six months later. Dermoscopy of a lesion on the trunk, which was increasing in size, showed a homogeneous brown pattern with irregularly arranged brown globules and dots at the center and periphery. Biopsy revealed a junctional nevus. Conclusion: The atypical brown pattern on dermoscopy of eruptive nevi is described for the first time, particularly after rituximab therapy.
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