镰状细胞病患者的肾动脉多普勒指数模式

IF 1.3 Q3 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING
Vivek Patre, Nobal Chandrakar
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引用次数: 0

摘要

目的:评估无实验室证据表明存在肾功能损害的镰状细胞病患者的肾动脉多普勒指数模式。材料与方法招募 50 名镰状细胞病(HbSS 表型)患者(镰状细胞病组)和 50 名对照组(对照组),进行病例对照研究。所有参与者均接受了超声波和彩色多普勒检查,并记录和比较了双肾主动脉、节段动脉和叶间动脉的搏动指数和阻力指数值。结果比较了对照组和镰状细胞病组肾主动脉、节段动脉和叶间动脉的多普勒测量值。结果发现,与对照组相比,镰状细胞病组肾主动脉、节段动脉和叶间动脉的搏动指数和阻力指数均明显升高(p 分别为 1.08(敏感性 72%,特异性 88%)和 >0.635(敏感性 66%,特异性 98%))。结论肾脏多普勒超声检查中的阻力指数和搏动指数值可作为镰状细胞病患者肾脏血管病变的早期放射学预测指标,但这些患者并没有肾功能损害的实验室证据。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
The pattern of renal artery Doppler indices in patients with sickle cell disease
Aim: To evaluate the pattern of renal artery Doppler indices in patients with sickle cell disease who do not have laboratory evidence of renal impairment. Material and methods: A case-control study was carried out after enrolling 50 patients with sickle cell disease (HbSS phenotype) (sickle cell disease group) and 50 con- trol subjects (control group). All the participants underwent ultrasound and color Doppler examination, and the pulsatility index and resistive index values of the main renal artery, segmental artery, and interlobar artery in both kidneys were recorded and compared. Results: The Doppler measurements of the main renal artery, segmental artery, and interlobar artery were compared between the control and sickle cell disease groups. It was found that both pulsatility index and resistive index were significantly higher in the sickle cell disease group, as compared to the control group, for the main renal artery, segmental artery, and interlobar artery (p <0.0001, p <0.0001, and p <0.0001, respectively). The optimal cut-off points for mean pulsatility index and resistive index, as measured by the Youden index, were found to be >1.08 (72% sensitivity and 88% specificity) and >0.635 (66% sensitivity and 98% specificity), respectively. Conclusions: Resistive index and pulsatility index values in renal Doppler sonography can serve as early radiologic predictors of renal vascular changes in sickle cell disease patients who do not have laboratory evidence of renal impairment.
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来源期刊
Journal of Ultrasonography
Journal of Ultrasonography RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING-
CiteScore
2.30
自引率
0.00%
发文量
58
审稿时长
20 weeks
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