无细胞淋巴瘤激酶阴性无细胞大细胞淋巴瘤

IF 0.2 Q4 DERMATOLOGY
Shraddha Kote, Samruddhi Chopkar, B. Supekar, J. Mukhi
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引用次数: 0

摘要

无细胞大细胞淋巴瘤(ALCL)是一种非霍奇金T细胞淋巴瘤,其特点是CD 30抗原持续表达,占非霍奇金淋巴瘤(NHL)的2-3%。ALCL 可表现为原发性皮肤病或继发皮肤受累的全身性疾病。世界卫生组织(WHO)将ALCL分为ALK阳性和ALK阴性ALCL。ALK阴性ALCL对治疗反应差,预后不良。由于相关文献较少,我们报告了一名58岁女性的局部侵袭性和转移性原发性皮肤无细胞淋巴瘤激酶阴性无细胞大细胞淋巴瘤。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Anaplastic lymphoma kinase-negative anaplastic large-cell lymphoma
Anaplastic large-cell lymphoma (ALCL) is a non-Hodgkin T-cell lymphoma characterized by persistent expression of CD 30 antigen that represents 2–3% of non-Hodgkin lymphoma (NHL). ALCL may present as a primary cutaneous disease or systemic disease with secondary cutaneous involvement. World Health Organization (WHO) classifies ALCL into ALK-positive and ALK-negative ALCL. ALK-negative ALCL shows poor response on treatment and has a bad prognosis. We report locally aggressive and metastasizing primary cutaneous anaplastic lymphoma kinase-negative anaplastic large-cell lymphoma in a 58-year-old female, due to its paucity of literature.
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