碳量子点浸渍玻璃离子黏合剂的性能评估,以避免种植体周围疾病。

IF 4.3 3区 材料科学 Q1 ENGINEERING, ELECTRICAL & ELECTRONIC
Febina Josephraj, Ashwin Kumar N, Vidyashree Nandini V, Sujatha S, V. Karthik
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引用次数: 0

摘要

牙科水门汀残留物会加剧种植体周围组织刺激和种植体周围炎。本研究旨在评估碳量子点(CQDs)浸渍玻璃离子水泥(GIC)的细胞毒性、物理化学、光学和流变学特性。使用柠檬酸通过热分解合成了表面钝化的荧光 CQDs,并将其与 GIC 混合。为了评估其性能,对其进行了表征研究和流变学测量。比较了用 GIC 和 GIC-CQD 粘结的 3D 打印牙科植入模型,分析了多余的粘结残留物。使用人牙髓干细胞(hDPSCs)进行 MTT 检测,并使用方差分析和 Tukey's 检验进行统计分析。合成了颗粒尺寸约为 2 nm 的 CQDs。XRD 证实了 GIC-CQD 的无定形性质。GIC-CQD 的荧光特性表明其发射强度是传统 GIC 的三倍。GIC-CQD 的熟化时间比 GIC 延长了 64 秒。在 5 至 10 厘米的紫外光激发下,可检测到 2 毫米大小的水泥残留物。生物相容性方面,稀释浓度为 0.125 毫克/毫升的 GIC-CQD 对 hDPSCs 的存活率超过 80%。我们首次报道了浸渍 CQDs 的 GIC 是一种独特而经济有效的策略,可使用手持设备原位快速检测过量水泥。这种新型的原位快速检测方法能让牙医在种植过程中识别出尺寸小于 2 毫米的残余骨水泥。因此,GIC-CQD 将取代传统的 GIC,有助于预防种植体周围疾病。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Performance evaluation of carbon quantum dots impregnated glass ionomer cement to avoid peri-implant disease.
Dental cement residues exacerbate peri-implant tissue irritation and peri-implantitis. The present study aims to evaluate the cytotoxicity, physiochemical, optical, and rheological properties of Carbon Quantum Dots (CQDs) impregnated Glass Ionomer Cement (GIC). Surface passivated fluorescent CQDs were synthesized using citric acid via thermal decomposition and blended with GIC. Characterization studies and rheological measurements were made to evaluate their performance. 3D-printed dental implant models cemented with GIC and GIC-CQD were compared to analyze excess cement residues. MTT assay was performed with human Dental Pulp Stem Cells (hDPSCs) and statistically analyzed using ANOVA and Tukey's test. CQDs with a particle dimension of ~2 nm were synthesized. The amorphous property of GIC-CQD was confirmed through XRD. The fluorescence properties of GIC-CQD showed three times higher emission intensity than conventional GIC. GIC-CQD attained maturation with a setting time extended by 64 seconds than GIC. Cement residue of size 2 mm was detected with a UV light excitation at a distance between 5 to 10 cm. Biocompatibility at 0.125 mg/ml dilution concentrations of GIC-CQD showed viability greater than 80% to hDPSCs. For the first time, we report that CQDs-impregnated GIC is a unique and cost-effective strategy for in-situ detection of excess cement rapidly using a hand-held device. A novel in-situ rapid detection method enables the dentist to identify residual cement of size less than 2 mm during the implantation. Therefore, GIC-CQD would replace conventional GIC and help in the prevention of peri-implant diseases.
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来源期刊
CiteScore
7.20
自引率
4.30%
发文量
567
期刊介绍: ACS Applied Electronic Materials is an interdisciplinary journal publishing original research covering all aspects of electronic materials. The journal is devoted to reports of new and original experimental and theoretical research of an applied nature that integrate knowledge in the areas of materials science, engineering, optics, physics, and chemistry into important applications of electronic materials. Sample research topics that span the journal's scope are inorganic, organic, ionic and polymeric materials with properties that include conducting, semiconducting, superconducting, insulating, dielectric, magnetic, optoelectronic, piezoelectric, ferroelectric and thermoelectric. Indexed/​Abstracted: Web of Science SCIE Scopus CAS INSPEC Portico
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