贲门失弛缓症的长期治疗效果:腹腔镜海勒肌切开术与 POEM 比较

IF 2.9 4区 医学 Q2 GASTROENTEROLOGY & HEPATOLOGY
Naoko Fukushima, Takahiro Masuda, Kazuto Tsuboi, Jun Watanabe, Fumiaki Yano
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引用次数: 0

摘要

贲门失弛缓症(Achalasia)是一种罕见的食管运动障碍疾病,其特征是食管下括约肌不松弛。腹腔镜海勒肌切开术(LHM)是治疗贲门失弛缓症的金标准。口周内镜下肌切开术(POEM)是一种创伤较小的治疗方法,目前已广泛开展,但对干预方法的选择至今仍存在争议。除了对短期疗效的广泛研究外,最近对 LHM 和 POEM 的长期疗效的研究也表明,经过 5 年的随访,两者的临床疗效相似。然而,与接受 LHM 的患者相比,接受 POEM 的患者更常见胃食管反流病(GERD)。此外,现有研究对不同疾病状态下的治疗效果进行了比较。一些研究表明,对于 III 型贲门失弛缓症患者来说,POEM 比 LHM 更优越,因为 POEM 允许进行更长的肌切术。有关乙状结肠型贲门失弛缓症治疗的研究目前正在进行中。然而,LHD 和 POEM 的长期比较结果并不充分,最佳治疗方法仍存在争议。还需要进一步的研究,治疗方案应与患者进行讨论,并根据患者的个人需求和病理情况量身定制。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Long-term outcomes of treatment for achalasia: Laparoscopic Heller myotomy versus POEM

Long-term outcomes of treatment for achalasia: Laparoscopic Heller myotomy versus POEM

Achalasia is a rare esophageal motility disorder characterized by nonrelaxation of the lower esophageal sphincter. Laparoscopic Heller myotomy (LHM) is the gold standard treatment for achalasia. Peroral endoscopic myotomy (POEM), a less invasive treatment, is performed extensively, and the selection of the intervention method remains debatable to date. In addition to the availability of extensive studies on short-term outcomes, recent studies on the long-term outcomes of LHM and POEM have shown similar clinical success after 5 y of follow-up. However, gastroesophageal reflux disease (GERD) was more common in patients who had undergone POEM than in those who had undergone LHM. Moreover, existing studies have compared treatment outcomes in various disease states. Some studies have suggested that POEM is superior to LHM for patients with type III achalasia because POEM allows for a longer myotomy. Research on treatment for sigmoid types is currently in progress. However, the long-term results comparing LHD and POEM are insufficient, and the best treatment remains controversial. Further research is needed, and treatment options should be discussed with patients and tailored to their individual needs and pathologies.

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来源期刊
Annals of Gastroenterological Surgery
Annals of Gastroenterological Surgery GASTROENTEROLOGY & HEPATOLOGY-
CiteScore
5.30
自引率
11.10%
发文量
98
审稿时长
11 weeks
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