2023 年亮点：胸腺 B 细胞--建立 T 细胞耐受性的重要参与者

IF 3.2 4区医学 Q3 CELL BIOLOGY

Immunology & Cell Biology Pub Date : 2024-04-22 DOI:10.1111/imcb.12761

Félix Lombard-Vadnais, Sylvie Lesage

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引用次数: 0

摘要

在这篇2023年亮点系列文章中，我们讨论了最近四篇研究小鼠和人类胸腺B细胞的文章。这些研究为这一独特的 B 细胞群的生物学提供了重要的新见解，从它们的活化和分化到它们在促进胸腺细胞的负性选择和产生调节性 T 细胞方面的作用。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

Highlight of 2023: Thymic B cells—important players in the establishment of T-cell tolerance

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Highlight of 2023: Thymic B cells—important players in the establishment of T-cell tolerance

In this article for the Highlights of 2023 Series, we discuss four recent articles that investigated thymic B cells, in both mice and humans. These studies provide important novel insights into the biology of this unique B-cell population, from their activation and differentiation to their role in promoting the negative selection of thymocytes and the generation of regulatory T cells.

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来源期刊

Immunology & Cell Biology 医学-免疫学

CiteScore

7.50

自引率

2.50%

发文量

审稿时长

4-8 weeks

期刊介绍： The Australasian Society for Immunology Incorporated (ASI) was created by the amalgamation in 1991 of the Australian Society for Immunology, formed in 1970, and the New Zealand Society for Immunology, formed in 1975. The aim of the Society is to encourage and support the discipline of immunology in the Australasian region. It is a broadly based Society, embracing clinical and experimental, cellular and molecular immunology in humans and animals. The Society provides a network for the exchange of information and for collaboration within Australia, New Zealand and overseas. ASI members have been prominent in advancing biological and medical research worldwide. We seek to encourage the study of immunology in Australia and New Zealand and are active in introducing young scientists to the discipline.