基于布林克曼指数的吸烟累积剂量与呼气峰流速之间的相关性

IF 1.8 Q2 MEDICINE, GENERAL & INTERNAL
Erwin Mulyawan MD, Sp.An, KMN, FIPM, PhD, Jessica Anastasia Setiawan MD
{"title":"基于布林克曼指数的吸烟累积剂量与呼气峰流速之间的相关性","authors":"Erwin Mulyawan MD, Sp.An, KMN, FIPM, PhD,&nbsp;Jessica Anastasia Setiawan MD","doi":"10.1002/jgf2.694","DOIUrl":null,"url":null,"abstract":"<div>\n \n \n <section>\n \n <h3> Background</h3>\n \n <p>Indonesia is the country with the highest prevalence of smokers above 15 years old according to WHO, with a percentage of 76.2%. Smoking-induced lung damage is characterized by inflammation, leading to the destruction of lung parenchyma and airway obstruction, ultimately worsening lung function parameters. This study aims to find correlation between cumulative dose of smoking based on Brinkman index (BI) with Peak Expiratory Flow Rate (PEFR).</p>\n </section>\n \n <section>\n \n <h3> Methods</h3>\n \n <p>This is a cross-sectional correlative study conducted on January–March 2020. Data were collected through history taking and PEFR measured with a peak flowmeter by taking the average of three peak flowmeter measurements, each separated by a 2-min interval. Inclusion criteria include male active smokers, aged 30 to 40 years, who have had a smoking history for at least 1 year. Exclusion criteria are as follows: uses e-cigarretes for smoking, has a history of chronic lung diseases such as tuberculosis, pneumonia, post-COVID-19 syndrome, asthma, and has not smoked in the last 28 days.</p>\n </section>\n \n <section>\n \n <h3> Results</h3>\n \n <p>A total of 48 male smokers are included in this study. The mean age of participants was 35.91 years, with a history of smoking of 18.12 years, and 12.5 cigarettes smoked daily. Patients included in this study had BI classified as mild (47.91%), moderate (47.91%), and severe (4.16%). PEFR in patients was classified into green (10.41%), yellow (83.33%), and red (6.25%). Analysis showed significant negative correlation between BI and PEFR (<i>r</i> = −0.721; <i>p</i> &lt; 0.001) suggesting that increasing Brinkman Index may lead to a decrease in PEFR.</p>\n </section>\n \n <section>\n \n <h3> Conclusion</h3>\n \n <p>Higher BI correlates with a decrease in PEFR. PEFR may prove to be useful in early detection of reduced pulmonary function. Further trials conducted on larger sample sizes and evaluating other lung function parameters are recommended.</p>\n </section>\n </div>","PeriodicalId":51861,"journal":{"name":"Journal of General and Family Medicine","volume":null,"pages":null},"PeriodicalIF":1.8000,"publicationDate":"2024-04-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/jgf2.694","citationCount":"0","resultStr":"{\"title\":\"The correlation between smoking cumulative dose based on Brinkman Index with peak expiratory flow rate\",\"authors\":\"Erwin Mulyawan MD, Sp.An, KMN, FIPM, PhD,&nbsp;Jessica Anastasia Setiawan MD\",\"doi\":\"10.1002/jgf2.694\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div>\\n \\n \\n <section>\\n \\n <h3> Background</h3>\\n \\n <p>Indonesia is the country with the highest prevalence of smokers above 15 years old according to WHO, with a percentage of 76.2%. Smoking-induced lung damage is characterized by inflammation, leading to the destruction of lung parenchyma and airway obstruction, ultimately worsening lung function parameters. This study aims to find correlation between cumulative dose of smoking based on Brinkman index (BI) with Peak Expiratory Flow Rate (PEFR).</p>\\n </section>\\n \\n <section>\\n \\n <h3> Methods</h3>\\n \\n <p>This is a cross-sectional correlative study conducted on January–March 2020. Data were collected through history taking and PEFR measured with a peak flowmeter by taking the average of three peak flowmeter measurements, each separated by a 2-min interval. Inclusion criteria include male active smokers, aged 30 to 40 years, who have had a smoking history for at least 1 year. Exclusion criteria are as follows: uses e-cigarretes for smoking, has a history of chronic lung diseases such as tuberculosis, pneumonia, post-COVID-19 syndrome, asthma, and has not smoked in the last 28 days.</p>\\n </section>\\n \\n <section>\\n \\n <h3> Results</h3>\\n \\n <p>A total of 48 male smokers are included in this study. The mean age of participants was 35.91 years, with a history of smoking of 18.12 years, and 12.5 cigarettes smoked daily. Patients included in this study had BI classified as mild (47.91%), moderate (47.91%), and severe (4.16%). PEFR in patients was classified into green (10.41%), yellow (83.33%), and red (6.25%). Analysis showed significant negative correlation between BI and PEFR (<i>r</i> = −0.721; <i>p</i> &lt; 0.001) suggesting that increasing Brinkman Index may lead to a decrease in PEFR.</p>\\n </section>\\n \\n <section>\\n \\n <h3> Conclusion</h3>\\n \\n <p>Higher BI correlates with a decrease in PEFR. PEFR may prove to be useful in early detection of reduced pulmonary function. Further trials conducted on larger sample sizes and evaluating other lung function parameters are recommended.</p>\\n </section>\\n </div>\",\"PeriodicalId\":51861,\"journal\":{\"name\":\"Journal of General and Family Medicine\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":1.8000,\"publicationDate\":\"2024-04-22\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://onlinelibrary.wiley.com/doi/epdf/10.1002/jgf2.694\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of General and Family Medicine\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://onlinelibrary.wiley.com/doi/10.1002/jgf2.694\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"MEDICINE, GENERAL & INTERNAL\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of General and Family Medicine","FirstCategoryId":"1085","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.1002/jgf2.694","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"MEDICINE, GENERAL & INTERNAL","Score":null,"Total":0}
引用次数: 0

摘要

印度尼西亚 15 岁以上吸烟者的比例最高。根据世卫组织的数据,这一比例为 76.2%。吸烟引起的肺损伤以炎症为特征,导致肺实质破坏和气道阻塞,最终使肺功能参数恶化。本研究旨在探讨根据布林克曼指数(BI)计算的吸烟与呼气峰流速(PEF)之间的相关性。布林克曼指数的计算方法是通过病史采集获得吸烟年限和吸烟量。呼气峰流速是通过三次峰值流量计测量的平均值得出的,每次测量间隔 2 分钟。纳入标准包括年龄在 30 至 40 岁之间、有至少 1 年吸烟史的男性活跃吸烟者。排除标准如下(1) 使用电子烟吸烟;(2) 有慢性肺部疾病史,如肺结核、肺炎、COVID-19 后综合征和哮喘;(3) 在过去 28 天内没有吸烟。参与者的平均年龄为 35.91 岁,吸烟史为 18.12 年,每天吸烟 12.5 支。本研究纳入的患者的 BI 分为轻度(47.91%)、中度(47.91%)和重度(4.16%)。患者的肺活量分为绿色(10.41%)、黄色(83.33%)和红色(6.25%)。分析显示,BI 与 PEFR 之间存在明显的负相关(r = -0.721;p < 0.001)。PEFR可能被证明有助于早期发现肺功能下降。建议在更大样本量上进行更多试验,并评估其他肺功能参数。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

The correlation between smoking cumulative dose based on Brinkman Index with peak expiratory flow rate

The correlation between smoking cumulative dose based on Brinkman Index with peak expiratory flow rate

Background

Indonesia is the country with the highest prevalence of smokers above 15 years old according to WHO, with a percentage of 76.2%. Smoking-induced lung damage is characterized by inflammation, leading to the destruction of lung parenchyma and airway obstruction, ultimately worsening lung function parameters. This study aims to find correlation between cumulative dose of smoking based on Brinkman index (BI) with Peak Expiratory Flow Rate (PEFR).

Methods

This is a cross-sectional correlative study conducted on January–March 2020. Data were collected through history taking and PEFR measured with a peak flowmeter by taking the average of three peak flowmeter measurements, each separated by a 2-min interval. Inclusion criteria include male active smokers, aged 30 to 40 years, who have had a smoking history for at least 1 year. Exclusion criteria are as follows: uses e-cigarretes for smoking, has a history of chronic lung diseases such as tuberculosis, pneumonia, post-COVID-19 syndrome, asthma, and has not smoked in the last 28 days.

Results

A total of 48 male smokers are included in this study. The mean age of participants was 35.91 years, with a history of smoking of 18.12 years, and 12.5 cigarettes smoked daily. Patients included in this study had BI classified as mild (47.91%), moderate (47.91%), and severe (4.16%). PEFR in patients was classified into green (10.41%), yellow (83.33%), and red (6.25%). Analysis showed significant negative correlation between BI and PEFR (r = −0.721; p < 0.001) suggesting that increasing Brinkman Index may lead to a decrease in PEFR.

Conclusion

Higher BI correlates with a decrease in PEFR. PEFR may prove to be useful in early detection of reduced pulmonary function. Further trials conducted on larger sample sizes and evaluating other lung function parameters are recommended.

求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
Journal of General and Family Medicine
Journal of General and Family Medicine MEDICINE, GENERAL & INTERNAL-
CiteScore
2.10
自引率
6.20%
发文量
79
审稿时长
48 weeks
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信