角膜白血病:罕见病例报告

Akshara Kharabanda, Sudhir Singh
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引用次数: 0

摘要

皮肤白血病是一种罕见的病例,其特征是肿瘤性白细胞(髓系或淋巴细胞)浸润临床上可识别的皮肤病变。它可以发生在白血病的血液学表现之前或病程中。病变的范围很广,从肉色到暴发性丘疹、结节或斑块不等。一名 52 岁的男性患者在过去 6 个月中因面部、躯干和四肢出现多处无症状红斑丘疹性皮损而来到皮肤科就诊。全身检查和计数正常。组织病理学检查显示,中性粒细胞和嗜酸性粒细胞在整个真皮层弥漫性密集浸润,并向网状真皮层间质扩展。浸润中散布着几个大细胞,细胞质丰富苍白,细胞核不规则。对患者进行了免疫组化检查,计划进行放射治疗,并向其解释了不良预后。由于该病例非常罕见,而且皮肤病理学家在早期诊断中起着重要作用,因此对该病例进行了报道。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Aleukemic leukemia cutis: a rare case report
Leukemia cutis is a rare case disorder characterised by infiltration of neoplastic leukocytes (myeloid or lymphoid) in clinically identifiable cutaneous lesions. It can occur before the onset of hematological presentation of leukemia or during the disease course. The lesions may be highly variable ranging from flesh coloured to violaceous papules, nodules or plaques. A 52-year-old male patient came to the Dermatology Department with multiple asymptomatic erythematous papulonodular lesions involving the face, trunk as well as the extremities from the past 6 months. Systemic examination and counts were normal. On histopathological examination diffuse dense infiltrate of neutrophils and eosinophils throughout the dermis with extension of infiltrate in the interstitium of reticular dermis. Scattered amidst the infiltrate were several large cells with abundant pale cytoplasm and irregular nuclei. Immunohistochemistry was done, radiotherapy was planned and poor prognosis was explained to the patient. The case is being reported due to its rarity and the role of dermatopathologist in early diagnosis.
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