手术前健康状况对青少年垂直袖状胃切除术后效果的影响。

IF 4.2 2区 医学 Q1 ENDOCRINOLOGY & METABOLISM
Obesity Pub Date : 2024-04-25 DOI:10.1002/oby.24018
Debi Swertfeger, Ahlee Kim, Hannah Sexmith, Maria E. Moreno-Fernandez, W. Sean Davidson, Michael Helmrath, Todd Jenkins, Tsuyoshi Okura, Esmond Geh, Stavra A. Xanthakos, Sara Szabo, Takahisa Nakamura, Senad Divanovic, Amy Sanghavi Shah
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引用次数: 0

摘要

目的:青少年在接受垂直袖带胃切除术(VSG)后,体重可下降 10% 至 50%。我们研究了在 VSG 术后 1 年,体重减轻超过平均水平 (AAWL) 的青少年与体重减轻低于平均水平 (BAWL) 的青少年在 VSG 术前的人口统计学或代谢参数是否存在差异,以及体重减轻低于平均水平的青少年在 VSG 术后 1 年是否仍能改善代谢健康。结果接受研究的 43 名青少年在 VSG 之前的平均年龄为 16.9 岁(标准差为 1.7 岁),其中 70% 为女性,19% 为非西班牙裔黑人,58% 为非西班牙裔白人,23% 为混血/其他种族。平均基线体重指数为 51.1 (SD 10.5) kg/m2。平均体重减轻 25.8%。AAWL 组减重 18.6 kg/m2(35.3%),而 BAWL 组减重 8.8 kg/m2(17.5%)。AAWL组和BAWL组基线时的体重指数、年龄、种族、性别和社会经济状况相似;但BAWL组在VSG前出现血糖异常、脂肪肝和血脂异常的频率更高。VSG 后 1 年时,BAWL 组中达到理想健康参数的青少年人数较少,他们的合并症缓解程度也较低。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Presurgery health influences outcomes following vertical sleeve gastrectomy in adolescents

Presurgery health influences outcomes following vertical sleeve gastrectomy in adolescents

Objective

Weight loss following vertical sleeve gastrectomy (VSG) in youth can range from 10% to 50%. We examined whether there are differences in demographic or metabolic parameters before VSG in youth who achieve above-average weight loss (AAWL) versus below-average weight loss (BAWL) at 1 year post VSG and if youth with BAWL still achieve metabolic health improvements at 1 year post VSG.

Methods

Demographic, anthropometric, and clinical lab data were collected before VSG and at 1, 3, 6, and 12 months after VSG.

Results

Forty-three youth with a mean age of 16.9 (SD 1.7) years before VSG were studied; 70% were female, 19% non-Hispanic Black, 58% non-Hispanic White, and 23% mixed/other race. Mean baseline BMI was 51.1 (SD 10.5) kg/m2. Average weight loss was 25.8%. The AAWL group lost 18.6 kg/m2 (35.3%) versus the BAWL group, who lost 8.8 kg/m2 (17.5%). BMI, age, race, sex, and socioeconomic status at baseline were similar between AAWL and BAWL groups; however, the BAWL group had a higher frequency of pre-VSG dysglycemia, steatotic liver disease, and dyslipidemia. At 1 year post VSG, fewer youth in the BAWL group achieved ideal health parameters, and they had less resolution of comorbidities.

Conclusions

The presence of comorbidities before VSG is associated with less weight loss and reduced resolution of metabolic conditions at 1 year post VSG.

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来源期刊
Obesity
Obesity 医学-内分泌学与代谢
CiteScore
11.70
自引率
1.40%
发文量
261
审稿时长
2-4 weeks
期刊介绍: Obesity is the official journal of The Obesity Society and is the premier source of information for increasing knowledge, fostering translational research from basic to population science, and promoting better treatment for people with obesity. Obesity publishes important peer-reviewed research and cutting-edge reviews, commentaries, and public health and medical developments.
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