下肢淋巴水肿的特征性单光子发射计算机断层扫描-计算机断层扫描结果:与吲哚菁绿淋巴造影的比较。

IF 16.4 1区 化学 Q1 CHEMISTRY, MULTIDISCIPLINARY
Hayahito Sakai, Toko Miyazaki, Maya Kanasaki, Reiko Tsukuura, Takumi Yamamoto
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引用次数: 0

摘要

导言:淋巴循环评估对下肢淋巴水肿(LEL)的治疗具有重要意义。单光子发射计算机断层扫描(SPECT-CT)已被引入淋巴水肿评估,但其特征性结果尚未完全明确。本研究旨在通过与吲哚菁绿(ICG)淋巴造影的结果对比,揭示继发性淋巴水肿的典型 SPECT-CT 结果。方法:这是一项单中心回顾性病例对照研究。研究人员查阅了因继发性淋巴结肿大而接受 SPECT-CT 和 ICG 淋巴造影检查的癌症幸存者的病历。将淋巴水肿肢体定义为ICG淋巴造影I-V期,非淋巴水肿肢体定义为ICG淋巴造影0期。确定了早期和延迟期的SPECT-CT特征性发现,并比较了淋巴水肿肢体和非淋巴水肿肢体的发现发生率。结果:本研究共纳入了 17 名患者的 34 个肢体,其中 6 个(17.6%)为非淋巴水肿肢体,28 个(82.4%)为淋巴水肿肢体。研究发现了四种特征性的 SPECT-CT 结果:小腿主淋巴通路延迟增强(DML)、少数腹股沟淋巴结延迟增强(FDN)、主淋巴通路早期不连续增强(EDM)和深部淋巴通路早期不增强(NDE)。在淋巴水肿肢体和非淋巴水肿肢体之间,FDN(64.3% 对 0%,P = 0.004)和 EDM(67.9% 对 0%,P = 0.002)差异有统计学意义。结论FDN和EDM是继发性LEL的特征性SPECT-CT结果。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Characteristic Single Photon Emission Computed Tomography-Computed Tomography Findings in Lower Extremity Lymphedema: Comparison to Indocyanine Green Lymphography.
Introduction: Evaluation of lymph circulation is significant in lower extremity lymphedema (LEL) management. Single-photon emission computed tomography-computed tomography (SPECT-CT) has been introduced for lymphedema evaluation, but its characteristic findings are yet fully clarified. The purpose of this study was to reveal typical SPECT-CT findings in secondary LEL by contrasting with indocyanine green (ICG) lymphography findings. Methods: This is a single-center retrospective case-control study. Medical charts of cancer survivors who underwent SPECT-CT and ICG lymphography for secondary LEL were reviewed. Lymphedematous limbs were defined as ICG lymphography stage I-V and non-lymphedematous limbs were defined as ICG lymphography stage 0. Characteristic SPECT-CT findings were identified in early phase and delay phase, and prevalence of the findings was compared between lymphedematous limbs and non-lymphedematous limbs. Results: Thirty-four limbs of 17 patients were included in this study; 6 (17.6%) non-lymphedematous limbs and 28 (82.4%) lymphedematous limbs. Four characteristic SPECT-CT findings were identified; delayed enhancement of the main lower leg lymphatic pathway (DML), few delayed inguinal lymph nodes enhancement (FDN), early phase discontinuous enhancement of the main lymphatic pathway (EDM), and nonenhancement of the deep lymphatic pathways in early phase (NDE). Between lymphedematous and non-lymphedematous limbs, there were statistically significant differences in FDN (64.3% vs. 0%, p = 0.004) and EDM (67.9% vs. 0%, p = 0.002). Conclusions: FDN and EDM are characteristic SPECT-CT findings in secondary LEL.
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来源期刊
Accounts of Chemical Research
Accounts of Chemical Research 化学-化学综合
CiteScore
31.40
自引率
1.10%
发文量
312
审稿时长
2 months
期刊介绍: Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.
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