精确的视听刺激时机征服化疗脑

IF 14.3 1区医学 Q1 ONCOLOGY

Trends in cancer Pub Date : 2024-04-21 DOI:10.1016/j.trecan.2024.04.002

Lindsey C. Mehl, Erin M. Gibson

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引用次数: 0

摘要

在最近的一项研究中，Kim 等人利用伽马诱导感官刺激（GENUS）挽救了顺铂和甲氨蝶呤化疗引起的认知障碍和神经胶质调节失调，特别是在化疗过程中和化疗后。GENUS 提供了一种治疗化疗脑的时间依赖性非侵入性方法，对解决神经退行性神经炎症具有更广泛的意义。

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Precise timing of audiovisual stimulation conquers chemobrain

In a recent study, Kim et al. utilized gamma entrainment using sensory stimuli (GENUS) to rescue cognitive impairment and glial dysregulation associated with cisplatin and methotrexate chemotherapy, specifically when applied both throughout and after chemotherapy administration. GENUS provides a time-dependent, non-invasive method for treating chemobrain, with broader implications for resolving neurodegenerative neuroinflammation.

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来源期刊

Trends in cancer Medicine-Oncology

CiteScore

28.50

自引率

0.50%

发文量

138

期刊介绍： Trends in Cancer, a part of the Trends review journals, delivers concise and engaging expert commentary on key research topics and cutting-edge advances in cancer discovery and medicine. Trends in Cancer serves as a unique platform for multidisciplinary information, fostering discussion and education for scientists, clinicians, policy makers, and patients & advocates.Covering various aspects, it presents opportunities, challenges, and impacts of basic, translational, and clinical findings, industry R&D, technology, innovation, ethics, and cancer policy and funding in an authoritative yet reader-friendly format.