系统性红斑狼疮患者的腿部溃疡及抗凝疗法的成功治疗

IF 1.5 4区医学 Q3 DERMATOLOGY

International Journal of Lower Extremity Wounds Pub Date : 2024-04-18 DOI:10.1177/15347346241248260

Öykü Gönüllü, Filiz C. Kahraman, Umut Mert Yıldırım

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引用次数: 0

摘要

在系统性红斑狼疮的特殊皮肤表现（如白细胞凝集性血管炎和血管病变）中，腿部溃疡的发生是罕见的，而且经常见于抗磷脂抗体阳性的患者。在此，我们报告了一名狼疮患者在抗凝治疗后腿部溃疡迅速愈合的病例，该患者无抗磷脂抗体阳性。与我们的病例一样，当免疫抑制剂对出现腿部溃疡的狼疮患者效果不佳时，使用抗凝剂进行辅助治疗可能是有益的。

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Leg Ulcers in a Patient With Systemic Lupus Erythematosus and Successful Treatment With Anticoagulant Therapy

Among specific skin manifestations of systemic lupus erythematosus such as leukocytoclastic vasculitis, and vasculopathy, the development of leg ulcers is rare and frequently seen in patients with antiphospholipid antibody positivity. Here we report the rapid healing of a leg ulcer without antiphospholipid antibody positivity in a patient with lupus in response to anticoagulant therapy. As in our case, when immunosuppressive agents are inadequate in lupus patients who develop leg ulcers, it may be beneficial to support the treatment with anticoagulants.

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来源期刊

International Journal of Lower Extremity Wounds DERMATOLOGY-SURGERY

CiteScore

4.60

自引率

17.60%

发文量

审稿时长

>12 weeks

期刊介绍： The International Journal of Lower Extremity Wounds (IJLEW) is a quarterly, peer-reviewed journal publishing original research, reviews of evidence-based diagnostic techniques and methods, disease and patient management, and surgical and medical therapeutics for lower extremity wounds such as burns, stomas, ulcers, fistulas, and traumatic wounds. IJLEW also offers evaluations of assessment and monitoring tools, dressings, gels, cleansers, pressure management, footwear/orthotics, casting, and bioengineered skin. This journal is a member of the Committee on Publication Ethics (COPE).