一例社区获得性潘通-瓦伦丁白细胞介素阳性耐甲氧西林金黄色葡萄球菌（MRSA）坏死性肺炎病例，使用两种抗 MRSA 药物治疗后获得成功

IF 0.8 Q4 RESPIRATORY SYSTEM

Respiratory Medicine Case Reports Pub Date : 2024-01-01 DOI:10.1016/j.rmcr.2024.102023

Ritsuya Shiiba, Masahiro Sano, Yoshihito Kogure, Hiroto Murao, Yuki Takigawa, Atsushi Torii, Arisa Yamada, Yuka Shinohara, Hideyuki Niwa, Chiyoe Kitagawa, Masahide Oki

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引用次数: 0

摘要

一名 22 岁的越南男子因咳嗽、呼吸困难和行动不便被转诊至我院。患者被诊断为社区获得性潘通-瓦伦丁白细胞介素阳性耐甲氧西林金黄色葡萄球菌（MRSA）菌血症和坏死性肺炎。治疗包括万古霉素（VCM）和美罗培南，MRSA菌血症有所好转。然而，肺组织的破坏仍在发展。因此，在万古霉素治疗方案中加入了利奈唑胺，这一干预措施使患者康复出院。在此，我们报告了一例患者接受两种抗 MRSA 药物联合治疗并治愈的病例。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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A case of community-acquired Panton-Valentine leukocidin-positive methicillin-resistant Staphylococcus aureus (MRSA) necrotizing pneumonia successfully treated with two anti-MRSA drugs

A 22-year-old Vietnamese man was referred to our hospital owing to cough, dyspnea, and difficulty moving. The patient was diagnosed with community-acquired Panton-Valentine leukocidin-positive methicillin-resistant Staphylococcus aureus (MRSA) bacteremia and necrotizing pneumonia. Treatment involved vancomycin (VCM) and meropenem, and the MRSA bacteremia improved. However, lung tissue destruction progressed. Therefore, linezolid was added to the VCM regimen, and this intervention led to the patient's recovery, and he was discharged from the hospital. Here, we report a case in which the patient was treated with a combination of two anti-MRSA drugs and was cured.

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