人参皂苷 Re 通过激活信号转导子和转录激活子 3 信号转导，减轻线粒体功能障碍，从而保护小鼠免受凯因酸盐诱发的神经毒性影响

IF 3.6 3区生物学 Q2 BIOCHEMISTRY & MOLECULAR BIOLOGY

Free Radical Research Pub Date : 2024-04-13 DOI:10.1080/10715762.2024.2341885

YenNhiDoan Nguyen, JiHoon Jeong, Naveen Sharma, Ngoc KimCuong Tran, Hoang-Yen Phi Tran, Duy-Khanh Dang, JungHoon Park, Jae Kyung Byun, Sung Kwon Ko, Seung-Yeol Nah, Hyoung-Chun Kim, Eun-Joo Shin

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引用次数: 0

摘要

研究表明，人参皂苷具有抗惊厥潜能，白细胞介素-6（IL-6）对凯因酸盐（KA）诱导的兴奋性毒性（一种颞叶癫痫模型）具有保护作用。人参...

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Ginsenoside Re protects against kainate-induced neurotoxicity in mice by attenuating mitochondrial dysfunction through activation of the signal transducers and activators of transcription 3 signaling

It was demonstrated that ginsenosides exert anti-convulsive potentials and interleukin-6 (IL-6) is protective from excitotoxicity induced by kainate (KA), a model of temporal lobe epilepsy. Ginseno...

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来源期刊

Free Radical Research 生物-生化与分子生物学

CiteScore

6.70

自引率

0.00%

发文量

审稿时长

3 months

期刊介绍： Free Radical Research publishes high-quality research papers, hypotheses and reviews in free radicals and other reactive species in biological, clinical, environmental and other systems; redox signalling; antioxidants, including diet-derived antioxidants and other relevant aspects of human nutrition; and oxidative damage, mechanisms and measurement.