准分子光（308 纳米）治疗慢性脓疱性苔藓的有效性和安全性

IF 2.5 4区医学 Q2 DERMATOLOGY

Photodermatology, photoimmunology & photomedicine Pub Date : 2024-04-15 DOI:10.1111/phpp.12964

Eman Mohamed Salah, Nermeen Ibrahim Bedair, Sarah Khalil Abd El‐Rahim, Mohammed Ahmed El‐Khalawany

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引用次数: 0

摘要

导言：慢性斑丘疹性苔藓是斑丘疹性苔藓的慢性病，它有多种形式的丘疹脓疱病。准分子光 308 是一种单色光，其波长在紫外线 B 波段内，可用于多种皮肤病的靶向光疗。方法34 名经组织病理学诊断为慢性斑癣的患者每两周接受一次准分子光 308 nm 治疗。结果31名患者完全痊愈，直到研究结束也没有复发，2名患者有部分反应，只有1名患者对治疗反应不佳。

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Efficacy and safety of excimer light (308 nm) in the treatment of pityriasis lichenoides chronica

IntroductionPityriasis lichenoides chronica is the chronic end of the spectrum of pityriasis lichenoides which have several forms of papulosuamous conditions. Several treatments obtained complete clearance of the condition including phototherapy and specifically narrow band ultraviolet B. The Excimer light 308 is a monochromatic light that acts within the ultraviolet B wavelength and used as a targeted phototherapy in several skin conditions.MethodsThirty‐four patients with histopathologically diagnosed pityriasis lichenoides chronica underwent treatment with biweekly sessions of excimer light 308 nm. Treatment continued until complete clearance was obtained or to a maximum of 48 sessions (24 weeks).ResultsThirty‐one patients obtained complete clearance with no recurrence till the end of the study period, two patients had partial response and only one patient showed poor response to treatment.ConclusionExcimer light can be a safe and effective treatment of pityriasis lichinoides chronica in different ages and genders.

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来源期刊

Photodermatology, photoimmunology & photomedicine 医学-皮肤病学

CiteScore

4.40

自引率

7.70%

发文量

审稿时长

6-12 weeks

期刊介绍： The journal is a forum for new information about the direct and distant effects of electromagnetic radiation (ultraviolet, visible and infrared) mediated through skin. The divisions of the editorial board reflect areas of specific interest: aging, carcinogenesis, immunology, instrumentation and optics, lasers, photodynamic therapy, photosensitivity, pigmentation and therapy. Photodermatology, Photoimmunology & Photomedicine includes original articles, reviews, communications and editorials. Original articles may include the investigation of experimental or pathological processes in humans or animals in vivo or the investigation of radiation effects in cells or tissues in vitro. Methodology need have no limitation; rather, it should be appropriate to the question addressed.