阿尔茨海默氏症易发区的低灌注与帕金森氏症的痴呆转化

IF 9.6 3区医学 Q1 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING

Clinical Nuclear Medicine Pub Date : 2024-04-08 DOI:10.1097/rlu.0000000000005211

Min Young Chun, Taein Lee, Su Hong Kim, Hye Sun Lee, Yun Joong Kim, Phil Hyu Lee, Young H Sohn, Yong Jeong, Seok Jong Chung

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引用次数: 0

摘要

尽管早期发现帕金森病（PD）患者中存在痴呆转化风险的个体非常重要，但对于预测未来认知能力下降的神经影像生物标志物仍未达成共识。我们旨在研究早期18F-N-（3-氟丙基）-2β-羧基甲氧基-3β-（4-碘苯基）正丙烷（18F-FP-CIT）PET上的脑灌注模式是否有可能作为帕金森病患者早期痴呆转换的神经影像预测指标。

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Hypoperfusion in Alzheimer's Disease-Prone Regions and Dementia Conversion in Parkinson's Disease.

Although early detection of individuals at risk of dementia conversion is important in patients with Parkinson's disease (PD), there is still no consensus on neuroimaging biomarkers for predicting future cognitive decline. We aimed to investigate whether cerebral perfusion patterns on early-phase 18F-N-(3-fluoropropyl)-2β-carboxymethoxy-3β-(4-iodophenyl) nortropane (18F-FP-CIT) PET have the potential to serve as a neuroimaging predictor for early dementia conversion in patients with PD.

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来源期刊

Clinical Nuclear Medicine 医学-核医学

CiteScore

2.90

自引率

31.10%

发文量

1113

审稿时长

2 months

期刊介绍： Clinical Nuclear Medicine is a comprehensive and current resource for professionals in the field of nuclear medicine. It caters to both generalists and specialists, offering valuable insights on how to effectively apply nuclear medicine techniques in various clinical scenarios. With a focus on timely dissemination of information, this journal covers the latest developments that impact all aspects of the specialty. Geared towards practitioners, Clinical Nuclear Medicine is the ultimate practice-oriented publication in the field of nuclear imaging. Its informative articles are complemented by numerous illustrations that demonstrate how physicians can seamlessly integrate the knowledge gained into their everyday practice.