Junxiong Zhang, Zhongxin Tian, Chao Qin, Mohammad Reza Momeni
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引用次数: 0
摘要
事实证明，经常进行体育锻炼可以促进个人的整体健康；现在的研究显示，这些变化伴随着表观遗传学的改变。事实证明，定期锻炼能使干预计划更加成功，并延长计划的坚持时间。说到表观遗传学的变化，主要有四个组成部分。这包括 DNA、组蛋白、特定非编码 RNA 的表达和 DNA 甲基化的变化。体力活动等外部触发因素可导致表观遗传成分的改变，从而引起转录过程的变化。本报告关注与运动后发生的表观遗传改变、受影响的基因以及由此产生的特征有关的现有知识。
The effects of exercise on epigenetic modifications: focus on DNA methylation, histone modifications and non-coding RNAs
Physical activity on a regular basis has been shown to bolster the overall wellness of an individual; research is now revealing that these changes are accompanied by epigenetic modifications. Regular exercise has been proven to make intervention plans more successful and prolong adherence to them. When it comes to epigenetic changes, there are four primary components. This includes changes to the DNA, histones, expression of particular non-coding RNAs and DNA methylation. External triggers, such as physical activity, can lead to modifications in the epigenetic components, resulting in changes in the transcription process. This report pays attention to the current knowledge that pertains to the epigenetic alterations that occur after exercise, the genes affected and the resulting characteristics.
期刊介绍：
Human Cell is the official English-language journal of the Japan Human Cell Society. The journal serves as a forum for international research on all aspects of the human cell, encompassing not only cell biology but also pathology, cytology, and oncology, including clinical oncology. Embryonic stem cells derived from animals, regenerative medicine using animal cells, and experimental animal models with implications for human diseases are covered as well.
Submissions in any of the following categories will be considered: Research Articles, Cell Lines, Rapid Communications, Reviews, and Letters to the Editor. A brief clinical case report focusing on cellular responses to pathological insults in human studies may also be submitted as a Letter to the Editor in a concise and short format.
Not only basic scientists but also gynecologists, oncologists, and other clinical scientists are welcome to submit work expressing new ideas or research using human cells.
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