{"title":"封底：一种源自红细胞的仿生微型机器人，能够分层适应全身给药过程中的五个关键阶段（EXP2 2/2024）","authors":"Ya-Xuan Zhu, Hao-Ran Jia, Yao-Wen Jiang, Yuxin Guo, Qiu-Yi Duan, Ke-Fei Xu, Bai-Hui Shan, Xiaoyang Liu, Xiaokai Chen, Fu-Gen Wu","doi":"10.1002/EXP.20240204","DOIUrl":null,"url":null,"abstract":"<p>An “all-in-one” red blood cell-derived microrobot is constructed to hierarchically overcome the different biological barriers during systemic drug delivery. The bionic microrobot can stably circulate in blood vessels, target the tumor under magnetic guidance, release therapeutic cargoes upon light triggering, and facilitate drug penetration in tumor by damaging extracellular matrix, thus realizing satisfactory anticancer therapeutic efficacy.\n\n <figure>\n <div><picture>\n <source></source></picture><p></p>\n </div>\n </figure></p>","PeriodicalId":72997,"journal":{"name":"Exploration (Beijing, China)","volume":"4 2","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2024-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/EXP.20240204","citationCount":"0","resultStr":"{\"title\":\"Back Cover: A red blood cell-derived bionic microrobot capable of hierarchically adapting to five critical stages in systemic drug delivery (EXP2 2/2024)\",\"authors\":\"Ya-Xuan Zhu, Hao-Ran Jia, Yao-Wen Jiang, Yuxin Guo, Qiu-Yi Duan, Ke-Fei Xu, Bai-Hui Shan, Xiaoyang Liu, Xiaokai Chen, Fu-Gen Wu\",\"doi\":\"10.1002/EXP.20240204\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p>An “all-in-one” red blood cell-derived microrobot is constructed to hierarchically overcome the different biological barriers during systemic drug delivery. The bionic microrobot can stably circulate in blood vessels, target the tumor under magnetic guidance, release therapeutic cargoes upon light triggering, and facilitate drug penetration in tumor by damaging extracellular matrix, thus realizing satisfactory anticancer therapeutic efficacy.\\n\\n <figure>\\n <div><picture>\\n <source></source></picture><p></p>\\n </div>\\n </figure></p>\",\"PeriodicalId\":72997,\"journal\":{\"name\":\"Exploration (Beijing, China)\",\"volume\":\"4 2\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2024-04-17\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://onlinelibrary.wiley.com/doi/epdf/10.1002/EXP.20240204\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Exploration (Beijing, China)\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://onlinelibrary.wiley.com/doi/10.1002/EXP.20240204\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Exploration (Beijing, China)","FirstCategoryId":"1085","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.1002/EXP.20240204","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Back Cover: A red blood cell-derived bionic microrobot capable of hierarchically adapting to five critical stages in systemic drug delivery (EXP2 2/2024)
An “all-in-one” red blood cell-derived microrobot is constructed to hierarchically overcome the different biological barriers during systemic drug delivery. The bionic microrobot can stably circulate in blood vessels, target the tumor under magnetic guidance, release therapeutic cargoes upon light triggering, and facilitate drug penetration in tumor by damaging extracellular matrix, thus realizing satisfactory anticancer therapeutic efficacy.
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