Muzamil Hussain , Shahzad Maqsood Khan , Muhammad Shafiq , Naseem Abbas
{"title":"基于聚乳酸的生物可降解材料在生物医学中的应用综述","authors":"Muzamil Hussain , Shahzad Maqsood Khan , Muhammad Shafiq , Naseem Abbas","doi":"10.1016/j.giant.2024.100261","DOIUrl":null,"url":null,"abstract":"<div><p>Polylactic Acid (PLA) is a biodegradable polymer gaining popularity as a replacement for conventional plastics in different industrial sectors. However, PLA has inherent limitations and requires modifications to enhance its performance. This review article covers the different important aspects related to the PLA such as the synthesis route of PLA, biodegradation mechanism of PLA, properties of PLA, and applications of PLA in different sectors. The main focus of this review is to identify the different innovative copolymers, blends and composites of PLA for biomedical applications. Most important characteristics such as degradation behavior, biocompatibility and mechanical properties of these PLA-based biodegradable polymers were briefly discussed. This review indicates that the optimization of processing techniques and suitable selection of additives play an important role to achieve the desired properties of PLA. This review also discusses the issues associated to PLA-based materials for biomedical applications.</p></div>","PeriodicalId":34151,"journal":{"name":"GIANT","volume":"18 ","pages":"Article 100261"},"PeriodicalIF":5.4000,"publicationDate":"2024-04-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2666542524000262/pdfft?md5=1a4b84a6cf903c05f028b53799daf19c&pid=1-s2.0-S2666542524000262-main.pdf","citationCount":"0","resultStr":"{\"title\":\"A review on PLA-based biodegradable materials for biomedical applications\",\"authors\":\"Muzamil Hussain , Shahzad Maqsood Khan , Muhammad Shafiq , Naseem Abbas\",\"doi\":\"10.1016/j.giant.2024.100261\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><p>Polylactic Acid (PLA) is a biodegradable polymer gaining popularity as a replacement for conventional plastics in different industrial sectors. However, PLA has inherent limitations and requires modifications to enhance its performance. This review article covers the different important aspects related to the PLA such as the synthesis route of PLA, biodegradation mechanism of PLA, properties of PLA, and applications of PLA in different sectors. The main focus of this review is to identify the different innovative copolymers, blends and composites of PLA for biomedical applications. Most important characteristics such as degradation behavior, biocompatibility and mechanical properties of these PLA-based biodegradable polymers were briefly discussed. This review indicates that the optimization of processing techniques and suitable selection of additives play an important role to achieve the desired properties of PLA. This review also discusses the issues associated to PLA-based materials for biomedical applications.</p></div>\",\"PeriodicalId\":34151,\"journal\":{\"name\":\"GIANT\",\"volume\":\"18 \",\"pages\":\"Article 100261\"},\"PeriodicalIF\":5.4000,\"publicationDate\":\"2024-04-04\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.sciencedirect.com/science/article/pii/S2666542524000262/pdfft?md5=1a4b84a6cf903c05f028b53799daf19c&pid=1-s2.0-S2666542524000262-main.pdf\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"GIANT\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S2666542524000262\",\"RegionNum\":1,\"RegionCategory\":\"化学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"CHEMISTRY, MULTIDISCIPLINARY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"GIANT","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2666542524000262","RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"CHEMISTRY, MULTIDISCIPLINARY","Score":null,"Total":0}
A review on PLA-based biodegradable materials for biomedical applications
Polylactic Acid (PLA) is a biodegradable polymer gaining popularity as a replacement for conventional plastics in different industrial sectors. However, PLA has inherent limitations and requires modifications to enhance its performance. This review article covers the different important aspects related to the PLA such as the synthesis route of PLA, biodegradation mechanism of PLA, properties of PLA, and applications of PLA in different sectors. The main focus of this review is to identify the different innovative copolymers, blends and composites of PLA for biomedical applications. Most important characteristics such as degradation behavior, biocompatibility and mechanical properties of these PLA-based biodegradable polymers were briefly discussed. This review indicates that the optimization of processing techniques and suitable selection of additives play an important role to achieve the desired properties of PLA. This review also discusses the issues associated to PLA-based materials for biomedical applications.
期刊介绍：
Giant is an interdisciplinary title focusing on fundamental and applied macromolecular science spanning all chemistry, physics, biology, and materials aspects of the field in the broadest sense. Key areas covered include macromolecular chemistry, supramolecular assembly, multiscale and multifunctional materials, organic-inorganic hybrid materials, biophysics, biomimetics and surface science. Core topics range from developments in synthesis, characterisation and assembly towards creating uniformly sized precision macromolecules with tailored properties, to the design and assembly of nanostructured materials in multiple dimensions, and further to the study of smart or living designer materials with tuneable multiscale properties.
求助内容：
应助结果提醒方式：
京公网安备 11010802042870号
