用 SIMPLE-seq 技术解码单细胞中 DNA 甲基化的动态变化

IF 39.1 1区生物学 Q1 GENETICS & HEREDITY

Nature Reviews Genetics Pub Date : 2024-04-12 DOI:10.1038/s41576-024-00729-7

Dongsheng Bai, Chenxu Zhu

引用次数: 0

摘要

在这篇 "贸易工具"（Tools of the Trade）文章中，白东升（Dongsheng Bai）和朱晨旭（Chenxu Zhu）介绍了一种可扩展的单细胞测序方法 SIMPLE-seq，该方法可同时解码胞嘧啶修饰 5mC 和 5hmC。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

SIMPLE-seq to decode DNA methylation dynamics in single cells

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SIMPLE-seq to decode DNA methylation dynamics in single cells

In this Tools of the Trade article, Dongsheng Bai and Chenxu Zhu describe SIMPLE-seq, a scalable single-cell sequencing method that simultaneously decodes the cytosine modifications 5mC and 5hmC.

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来源期刊

Nature Reviews Genetics 生物-遗传学

CiteScore

57.40

自引率

0.50%

发文量

113

审稿时长

6-12 weeks

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