使用 C18 柱串联多糖手性色谱柱分离四对生物碱对映体

IF 4.3 3区 材料科学 Q1 ENGINEERING, ELECTRICAL & ELECTRONIC
Xiaoxi Si, Yu Tian, Shu-Teng Xu, Chunbo Liu, Zhenjie Li, Ji Yang, Ying Guan, Yangzhou Xie, Xiaoqing Shi, Zhigang Xu, Zhihua Liu
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引用次数: 0

摘要

生物碱对映体具有不同的生理和药理作用,不同的手性组成对卷烟的感官和使用安全性有很大影响。研究不同构型的生物碱对映体对卷烟感官的影响对烟草产品的开发具有重要意义,但生物碱对映体的手性分离成为核心问题。本文研究了如何应用 C18 色谱柱和多糖手性色谱柱分离检测不同品牌烟草和卷烟中的四对生物碱对映体。结果表明,这两种色谱柱的串联技术实现了四对生物碱对映体的基线分离。不同烟草样品中生物碱对映体的解析含量和比例不同,表现出不同的手性分布特征。根据生物碱对映体的不同分布特征,可以区分不同品牌的烟草样品,鉴别真假卷烟。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Enantiomeric separation of four pairs of alkaloids by using a C18 column tandem polysaccharide-based chiral column
Alkaloid enantiomers have different physiological and pharmacological effects, and different chiral compositions have a large impact on cigarette sensory and use safety. Studying the effects of different configurations of alkaloid enantiomers on cigarette sensory is important for the development of tobacco products, but the chiral separation of alkaloid enantiomers has become the core problem. Here, the application of a C18 column coupled with a polysaccharide-based chiral column to separate and detect four pairs of alkaloid enantiomers in tobacco and cigarette smoke of different brands was investigated. Results showed that the tandem technology of the two columns enabled the baseline separation of four pairs of alkaloid enantiomers. The resolution of enantiomers of alkaloids in different tobacco samples differed in content and ratio, showing different chiral distribution characteristics. According to the different distribution characteristics of alkaloid enantiomers, tobacco samples of different brands can be distinguished and real cigarettes can be identified.
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来源期刊
CiteScore
7.20
自引率
4.30%
发文量
567
期刊介绍: ACS Applied Electronic Materials is an interdisciplinary journal publishing original research covering all aspects of electronic materials. The journal is devoted to reports of new and original experimental and theoretical research of an applied nature that integrate knowledge in the areas of materials science, engineering, optics, physics, and chemistry into important applications of electronic materials. Sample research topics that span the journal's scope are inorganic, organic, ionic and polymeric materials with properties that include conducting, semiconducting, superconducting, insulating, dielectric, magnetic, optoelectronic, piezoelectric, ferroelectric and thermoelectric. Indexed/​Abstracted: Web of Science SCIE Scopus CAS INSPEC Portico
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