{"title":"生化标记在筛查宫颈上皮病变中的作用与 p16ink4a 蛋白表达的测定","authors":"D. Mamarasulova","doi":"10.37547/tajmspr/volume06issue01-07","DOIUrl":null,"url":null,"abstract":"This article describes the role of biochemical markers in the pathology of the cervical epithelium. In research 10716 women aged 25-65 years were examined (mean age 43.28±3.82 years). And in the course of the study, it was found that the expression of the P16INK4A protein by cervical epithelial cells increases the risk of epithelial metaplasia of any degree by 8.86 times, high-grade epithelial metaplasia - by 692 times, RMS by 48 times.","PeriodicalId":494509,"journal":{"name":"The American journal of medical sciences and pharmaceutical research","volume":"4 4","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"THE ROLE OF BIOCHEMICAL MARKERS IN SCREENING OF CERVICAL EPITHELIAL PATHOLOGY WITH DETERMINATION OF P16INK4A PROTEIN EXPRESSION\",\"authors\":\"D. Mamarasulova\",\"doi\":\"10.37547/tajmspr/volume06issue01-07\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"This article describes the role of biochemical markers in the pathology of the cervical epithelium. In research 10716 women aged 25-65 years were examined (mean age 43.28±3.82 years). And in the course of the study, it was found that the expression of the P16INK4A protein by cervical epithelial cells increases the risk of epithelial metaplasia of any degree by 8.86 times, high-grade epithelial metaplasia - by 692 times, RMS by 48 times.\",\"PeriodicalId\":494509,\"journal\":{\"name\":\"The American journal of medical sciences and pharmaceutical research\",\"volume\":\"4 4\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2024-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"The American journal of medical sciences and pharmaceutical research\",\"FirstCategoryId\":\"0\",\"ListUrlMain\":\"https://doi.org/10.37547/tajmspr/volume06issue01-07\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"The American journal of medical sciences and pharmaceutical research","FirstCategoryId":"0","ListUrlMain":"https://doi.org/10.37547/tajmspr/volume06issue01-07","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
THE ROLE OF BIOCHEMICAL MARKERS IN SCREENING OF CERVICAL EPITHELIAL PATHOLOGY WITH DETERMINATION OF P16INK4A PROTEIN EXPRESSION
This article describes the role of biochemical markers in the pathology of the cervical epithelium. In research 10716 women aged 25-65 years were examined (mean age 43.28±3.82 years). And in the course of the study, it was found that the expression of the P16INK4A protein by cervical epithelial cells increases the risk of epithelial metaplasia of any degree by 8.86 times, high-grade epithelial metaplasia - by 692 times, RMS by 48 times.
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