肠道微生物组和代谢组发生变化后:大肠癌的早期检测机会

Mehdi Pezeshgi Modarres, Mohamad Amin Habibi, M. Pashaei, Yousef Mohammadpour, Kimia Jazi, S. Ahmadpour
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引用次数: 0

摘要

结肠直肠癌(CRC)是一种常见的癌症,导致全球无数人死亡。近几十年来,技术的进步促使人们开始考虑 CRC 发病机制的分子途径。一些研究发现了 CRC 所涉及的各种机制,并为新疗法和早期诊断铺平了道路。肠道微生物在肠道炎症中起着至关重要的作用,并可能与结肠炎结直肠癌有关。在这篇综述中,我们阐述了微生物组群及其代谢组谱作为早期检测 CRC 的新筛选方法的作用。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Alterations of the Gut Microbiome and Metabolome Following: A Opportunity for Early Detection of Colorectal Cancer
Colorectal cancer (CRC) is a commonly diagnosed cancer responsible for numerous deaths worldwide. In recent decades, technological advances implicated in considering the molecular pathways underlying CRC pathogenesis. Several investigations have identified various mechanisms involved in CRC and have paved the way for new therapeutics and early diagnosis. Gut microbiome play a crucial role in intestinal inflammation and can be associated with colitis colorectal cancer. In this review, we narrated the role of the microbiome population and their metabolome profile as a new screening method for early detection of CRC.
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