腹主动脉无配对内脏分支的动脉粥样硬化(临床和仪器诊断学)

A. Shuleshova, A. A. Lisitsa, D. V. Danilov, A. E. Komlev
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引用次数: 0

摘要

目的确定腹主动脉非配对内脏动脉分支动脉粥样硬化病变的发病率。探讨上消化道黏膜的临床表现特征和状态。材料和方法共研究了 118 名腹主动脉非配对内脏动脉分支动脉粥样硬化患者,年龄在 45-89 岁之间。对比组包括 120 名腹主动脉未配对内脏动脉分支未发生动脉粥样硬化的患者。两组患者均有冠状动脉粥样硬化。超声多普勒成像(USDG)作为筛查技术,CT血管造影和MSCT主动脉造影用于验证腹主动脉非配对内脏动脉分支的闭塞-狭窄病变。通过临床症状和内镜检查结果确诊胃黏膜糜烂病变。结果在我们的研究中,28.8%的患者发现了与血流动力学相关的狭窄(>70%)。肠系膜血管粥样血栓形成的临床表现无特异性。腹痛是腹型心绞痛患者最常见的症状(76.3%)。对确诊为慢性腹部缺血(CAI)的患者进行的上消化道内窥镜检查显示,100%的病例都出现了胃黏膜萎缩(局灶性或弥漫性)。55.1%的患者发现胃糜烂。27.1%的患者出现胃溃疡。胃黏膜的侵蚀性和溃疡性病变与黏膜的萎缩性变化结合在一起。28.8%的患者患有腐蚀性食管炎。食管粘膜病灶异常的检出率为 27.3%,胃粘膜病灶异常的检出率为 54.2%,主要由肠化生引起。结论由于闭塞性血管疾病的发病率越来越高,早期发现上消化道病变仍是一项紧迫的挑战。使用额外的内镜 NBI 和 ZOOM 技术进行全面的内镜检查,可以识别粘膜的所有变化,包括小的病灶异常。及时发现疾病,才能选择正确的治疗方法。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Atherosclerosis of unpaired visceral branches of the abdominal aorta (clinical and instrumental diagnostics)
Aim. To establish the prevalence of atherosclerotic lesions in the unpaired visceral artery branches of the abdominal aorta. To explore the features of clinical presentation, the state of the mucosa of the upper GI tract. Materials and methods. A total of 118 patients with atherosclerosis of the unpaired visceral artery branches of the abdominal aorta aged 45 to 89 years were examined. The comparison group included 120 patients without atherosclerosis in the unpaired visceral artery branches of the abdominal aorta. Patients in both groups had coronary atherosclerosis. Ultrasound dopplerography (USDG) as a screening technique, CT angiography, and MSCT aortography were used to verify occlusion-stenotic lesions in the unpaired visceral artery branches of the abdominal aorta. The diagnosis of erosion changes in the gastric mucosa was confirmed by clinical symptoms and endoscopic examination findings. Results. In our study, hemodynamically relevant stenosis (>70%) was identified in 28.8% of patients. The clinical presentation of atherothrombosis in mesenteric vessels was shown to be nonspecific. Abdominal pain was the most common symptom in the examined patients with abdominal angina (76.3%). The upper GI endoscopy in patients with a verified diagnosis of chronic abdominal ishemia (CAI) showed gastric mucosa atrophy (focal or diffuse) in 100% of cases. Gastric erosions are identified in 55.1% of patients. Gastric ulcers are observed in 27.1% of patients. Erosive and ulcerative lesions of the gastric mucosa are combined with atrophic changes in the mucosa. Erosive esophagitis was detected in 28.8% of patients. The frequency of detected focal abnormalities in the esophageal mucosa accounts for 27.3%, and those in the gastric mucosa is 54.2%, mainly due to intestinal metaplasia. Conclusion. Due to the increasing prevalence of obliterative vascular diseases, early detection of changes in the upper gastrointestinal tract remains an urgent challenge. The comprehensive endoscopic examination using additional endoscopic NBI and ZOOM techniques allows to identify all changes in the mucosa, including small focal abnormalities. Timely detection of the disease makes it possible to choose the right treatment method.
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