基于食物的营养干预对肯尼亚布西亚县医院艾滋病毒感染者非传染性疾病管理的影响

Q3 Social Sciences

African Journal of Food, Agriculture, Nutrition and Development Pub Date : 2024-01-29 DOI:10.18697/ajfand.126.23955

R. Akelola, E. Wamukoya, J. Situma

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引用次数: 0

摘要

良好的营养可优化抗逆转录病毒疗法（ART）的疗效并提高治疗依从性，从而延长艾滋病毒携带者的生命（NASCOP，2014 年），但如果没有适当的护理和管理，他们将面临非传染性疾病（NCDs）的威胁。关键目标：确定食物营养干预对布西亚艾滋病毒携带者非传染性疾病管理的影响。实验设计采用随机对照试验方法。对照组有 30 名受试者，以 Plumpy'nut 为食；治疗组有 30 名受试者，以 Power Porridge (PROLCARMIV) 为食，为期 60 天。研究对象从肯尼亚布西亚县转诊医院的综合护理诊所（CCC）有目的性地挑选出来，并采用简单随机抽样法随机选出研究对象，平均分配到各组。采用结构化问卷收集数据，并使用统计科学社会软件包 26 版进行分析。NCDS患病率；75.5%的高血压患者；15.6%的糖尿病患者和8.9%的心脏病患者；干预后干预组的体重指数增加；实验室分析；干预后血红蛋白结果；与对照组（12.69，SD=1.24）相比，干预组的平均水平更高（M=13.62，SD=2.69），P值=0.487，P值=0.471。对照组随机血糖（RBS）较高（5.96，SD=1.70），P 值= <0.001；干预组（M=5.79，SD=1.02），P 值= <0.001。干预后的肝功能检测；TB、AST 和 ALT 显示出更高的 SD 值，表明存在变异。血脂概况显示，对照组的 TC 平均值为 4.39（0.95）；干预组的 TC 平均值为 3.78（0.94）：P=0.017；对照组的 HDL 平均值为 1.58（0.57）：干预组的 HDL 平均值为 1.14（0.53），P=0.036；对照组的 TG 平均值为 1.50（0.50）：干预组的 TG 平均值为 1.14：（0.46），P=0.017：对照组的低密度脂蛋白平均值为 2.26（0.66）：干预组的低密度脂蛋白平均值为 1.43（0.42），p= 0.041：总胆固醇、高密度脂蛋白、总胆固醇和低密度脂蛋白均显著下降。肾功能检测；两组间无明显差异。结论；PROLCARMIV 的依从性为 82.5%，吸引了更多人接受 CCC 服务。PROLCARMIV可以控制PLHIV中的非传染性疾病，回答了替代假设，这将为政策提供参考。关键字食物营养干预、艾滋病毒、非传染性疾病、PLHIV、PROLCARMIV、强力粥

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Effect of food-based nutrition intervention on management of non-communicable diseases among people living with HIV in Busia County hospital, Kenya

Good nutrition optimizes benefits of ART (Antiretroviral therapy) and increases treatment adherence, both prolongs lives of PLHIV (NASCOP, 2014), without proper care and management it exposes them to non-communicable diseases (NCDs). Key objective; to determine the effect of food-based nutrition intervention on the management of NCDs among PLHIV in Busia. The design was experimental using randomized control trial approach. The control group had 30 subjects who were fed on Plumpy‘nut while treatment group had 30 subjects who were fed on Power Porridge (PROLCARMIV), for 60 days. Subjects were purposively selected from the Comprehensive Care Clinic (CCC) in Busia County referral hospital- Kenya, further study subjects were randomly selected using simple random sampling, assigned equally to each group. Data were collected using a structured questionnaire analyzed using Social Package for Statistical Sciences version 26. Prevalence of NCDS; 75.5% hypertension; 15.6% diabetes and 8.9% heart disease; post-intervention BMI for intervention group increased; laboratory analyses; Hb post–intervention results; mean levels were higher in intervention group (M=13.62, SD=2.69) p-value = 0.487 compared to control group (12.69, SD=1.24), p value= 0.471. Random Blood Sugar (RBS) were higher in control group (5.96, SD=1.70), with p value= <0.001, intervention group (M=5.79, SD=1.02), with p-value = <0.001. Post-intervention liver function test; TB, AST, and ALT showed higher SD indicating variability. Lipid profile; showed TC mean (4.39 (0.95) for control group; a mean of 3.78(0.94) for the intervention group: p=0.017; HDL for the control group with a mean of 1.58(0.57): mean of 1.14 (0.53) for the intervention group with p=0.036: TG for the control group, mean of 1.50 (0.50): for the intervention group with p= 0.017: mean of 1.14: (0.46): LDL for control group with a mean of 2.26 (0.66): mean of 1.43 (0.42): for the intervention group with p= 0.041: TC, HDL, TG, and LDL all exhibited significant decreases. Kidney function tests; no significant differences between the two groups. Conclusion; Compliance for PROLCARMIV; 82.5%, attracting uptake of CCC services. PROLCARMIV can manage NCDs among PLHIV, answering the alternative hypothesis, this would inform policy. Key words: Food-Based Nutrition Intervention, HIV, NCDs, PLHIV, PROLCARMIV, Power Porridge

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来源期刊

African Journal of Food, Agriculture, Nutrition and Development Agricultural and Biological Sciences-Agricultural and Biological Sciences (miscellaneous)

CiteScore

0.90

自引率

0.00%

发文量

124

审稿时长

24 weeks

期刊介绍： The African Journal of Food, Agriculture, Nutrition and Development (AJFAND) is a highly cited and prestigious quarterly peer reviewed journal with a global reputation, published in Kenya by the Africa Scholarly Science Communications Trust (ASSCAT). Our internationally recognized publishing programme covers a wide range of scientific and development disciplines, including agriculture, food, nutrition, environmental management and sustainable development related information.